Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TRPA1 | O75762 | 6/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5050147 | 0.73 | TRPA1 (0.58) | TRPA1 | |
| SCHEMBL29633894 | 0.73 | — | — | |
| SCHEMBL9926021 | 0.73 | TRPA1 (0.58) | TRPA1 | |
| SCHEMBL15075855 | 0.73 | — | — | |
| SCHEMBL30691872 | 0.73 | TRPA1 (0.58) | TRPA1 | |
| SCHEMBL2936989 | 0.69 | TRPA1 (0.40) | TRPA1 | |
| SCHEMBL789562 | 0.68 | TRPA1 (0.38) | TRPA1 | |
| SCHEMBL3109349 | 0.68 | TRPA1 (0.38) | TRPA1 | |
| SCHEMBL3092895 | 0.67 | TRPA1 (0.31) | TRPA1 | |
| SCHEMBL2908519 | 0.67 | TRPA1 (0.31) | TRPA1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 31 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-11312668-B2 | Organic reactions carried out in aqueous solution in the presence of a hydroxyalkyl(alkyl)cellulose or an alkylcellulose | ABBVIE INC. (US) | 2022-04-26 | — | — | US | disclosed |
| US-11001698-B2 | Stabilizer composition | BASF SE | 2021-05-11 | — | — | US | disclosed |
| US-20210017100-A1 | ORGANIC REACTIONS CARRIED OUT IN AQUEOUS SOLUTION IN THE PRESENCE OF A HYDROXYALKYL(ALKYL)CELLULOSE OR AN ALKYLCELLULOSE | AbbVie Deutschland GmbH & Co. KG (DE) | 2021-01-21 | — | — | US | disclosed |
| US-10836688-B2 | Organic reactions carried out in aqueous solution in the presence of a hydroxyalkyl(alkyl)cellulose or an alkylcellulose | ABBVIE INC. (US) | 2020-11-17 | — | — | US | disclosed |
| US-10683256-B2 | Process for preparing substituted biphenyls | BASF SE (DE) | 2020-06-16 | — | — | US | disclosed |
| US-20200148610-A1 | ORGANIC REACTIONS CARRIED OUT IN AQUEOUS SOLUTION IN THE PRESENCE OF A HYDROXYALKYL(ALKYL)CELLULOSE OR AN ALKYLCELLULOSE | ABBVIE INC. | 2020-05-14 | — | — | US | disclosed |
| US-20200048431-A1 | STABILIZER COMPOSITION | BASF SE (DE) | 2020-02-13 | — | — | US | disclosed |
| US-20200048394-A1 | HARDENABLE POLYMER COMPOSITION | BASF SE (DE) | 2020-02-13 | — | — | US | disclosed |
| US-10555952-B2 | Pharmaceutical compositions and methods for anesthesiological applications | MELT PHARMACEUTICALS, INC. (US) | 2020-02-11 | — | — | US | disclosed |
| EP-3115361-B1 | HETEROCYCLIC COMPOUNDS, AND PREPARATION METHOD AND USE THEREOF | SHANGHAI INST MATERIA MEDICA CAS (CN) | 2019-10-23 | — | — | EP | disclosed |
| US-20150299132-A1 | AROMATIC IMIDE COMPOUND AND METHOD FOR PRODUCING SAME | AZ ELECTRONIC MATERIALS (LUXEMBOURG) S.A.R.L. (US) | 2015-10-22 | — | — | US | disclosed |
| US-20150299132-A1 | AROMATIC IMIDE COMPOUND AND METHOD FOR PRODUCING SAME | AZ ELECTRONIC MATERIALS (LUXEMBOURG) S.A.R.L. (US) | 2015-10-22 | — | — | US | disclosed |
| WO-2015131856-A1 | HETEROCYCLIC COMPOUNDS, AND PREPARATION METHOD AND USE THEREOF | 中国科学院上海药物研究所 | 2015-09-11 | — | — | WO | disclosed |
| US-5169850-A | Neurotropic or hypotensive agents | AMERICAN CYANAMID COMPANY (US) | 1992-12-08 | — | — | US | disclosed |
| US-5141735-A | Viricides for AIDS treatment | HOFFMAN-LA ROCHE, INC. (US) | 1992-08-25 | — | — | US | disclosed |
| EP-0031561-B1 | A RECTALLY ADMINISTERED SUPPOSITORY COMPRISING A DRUG AND AN ADJUVANT | MERCK & CO. INC. (US) | 1985-04-10 | — | — | EP | disclosed |
| US-4145417-A | TRANQUILIZERS, SEDATIVES, HYPNOTICS, ADDUCTS WITH ALDEHYDES | DDSA PHARMACEUTICLAS LTD. (GB) | 1979-03-20 | — | — | US | disclosed |
| US-4060608-A | TRANQUILIZERS, SEDATIVE, HYPNOSIS INDUCER | DDSA PHARMACEUTICALS (EN) | 1977-11-29 | — | — | US | disclosed |
| US-4006135-A | Hydroxymethyl benzodiazepine derivatives | DDSA PHARMACEUTICALS (EN) | 1977-02-01 | — | — | US | disclosed |
| US-3932399-A | MUSCLE RELAXANTS, SEDATIVES, ANTICONVULSANTS | HOFFMANN-LA ROCHE INC. (US) | 1976-01-13 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (7 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-10683256-B2 | Process for preparing substituted biphenyls | PIK3CA, PIK3CB, PIK3CG | TRPA1 2966/4885 |
| US-20210017100-A1 | ORGANIC REACTIONS CARRIED OUT IN AQUEOUS SOLUTION IN THE PRESENCE OF A HYDROXYALKYL(ALKYL)CELLULOSE OR AN ALKYLCELLULOSE | LIPA, ALG1, CEL | TRPA1 3258/4885 |
| US-10555952-B2 | Pharmaceutical compositions and methods for anesthesiological applications | GRIN2B, GRIN3A, GABRA5 | TRPA1 238/4885 |
| US-20200148610-A1 | ORGANIC REACTIONS CARRIED OUT IN AQUEOUS SOLUTION IN THE PRESENCE OF A HYDROXYALKYL(ALKYL)CELLULOSE OR AN ALKYLCELLULOSE | LIPA, ALG1, CEL | TRPA1 3258/4885 |
| US-10836688-B2 | Organic reactions carried out in aqueous solution in the presence of a hydroxyalkyl(alkyl)cellulose or an alkylcellulose | LIPA, ALG1, CEL | TRPA1 3258/4885 |
| US-11312668-B2 | Organic reactions carried out in aqueous solution in the presence of a hydroxyalkyl(alkyl)cellulose or an alkylcellulose | LIPA, ALG1, CEL | TRPA1 3258/4885 |
| US-20150299132-A1 | AROMATIC IMIDE COMPOUND AND METHOD FOR PRODUCING SAME | H1-0, H4C1; H4C2; H4C3; H4C4; H4C5; H4C6; H4C8; H4C9; H4C11; H4C12; H4C13; H4C14; H4C15; H4C16, HRH4 | TRPA1 93/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.