Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 4/20 | 0.61 |
| ▸ | NPC1 | O15118 | 4/20 | 0.61 |
| ▸ | RAB9A | P51151 | 4/20 | 0.61 |
| ▸ | MEN1 | O00255 | 3/20 | 0.61 |
| ▸ | ALDH1A1 | P00352 | 8/20 | 0.58 |
| ▸ | EPHX1 | P07099 | 2/20 | 0.58 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.58 |
| ▸ | KDM4E | B2RXH2 | 7/20 | 0.58 |
| ▸ | HPGD | P15428 | 3/20 | 0.57 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.57 |
| ▸ | MAPT | P10636 | 4/20 | 0.56 |
| ▸ | ALOX12 | P18054 | 3/20 | 0.56 |
| ▸ | PDCD1 | Q15116 | 1/20 | 0.55 |
| ▸ | CD274 | Q9NZQ7 | 1/20 | 0.55 |
| ▸ | AGTR1 | P30556 | 1/20 | 0.54 |
| ▸ | LMNA | P02545 | 2/20 | 0.53 |
| ▸ | HTT | P42858 | 1/20 | 0.53 |
| ▸ | GAA | P10253 | 1/20 | 0.53 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.52 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.52 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9728074 | 0.89 | ALDH1A1 (0.70) | KMT2ANPC1RAB9AMEN1ALDH1A1 | |
| SCHEMBL9728569 | 0.86 | ALDH1A1 (0.74) | KMT2ANPC1RAB9AMEN1ALDH1A1 | |
| SCHEMBL11826793 | 0.86 | PDCD1 (0.72) | KMT2ANPC1RAB9AMEN1ALDH1A1 | |
| SCHEMBL9728350 | 0.83 | ALDH1A1 (0.70) | KMT2ANPC1RAB9AMEN1ALDH1A1 | |
| SCHEMBL14096473 | 0.81 | NPC1 (0.79) | KMT2ANPC1RAB9AMEN1ALDH1A1 | |
| SCHEMBL3057942 | 0.81 | NPC1 (0.64) | KMT2ANPC1RAB9AMEN1ALDH1A1 | |
| SCHEMBL3053910 | 0.78 | ALDH1A1 (0.62) | KMT2ANPC1RAB9AMEN1ALDH1A1 | |
| SCHEMBL14865820 | 0.78 | NPC1 (0.61) | KMT2ANPC1RAB9AMEN1ALDH1A1 | |
| SCHEMBL9729024 | 0.78 | ALDH1A1 (0.80) | KMT2ANPC1RAB9AMEN1ALDH1A1 | |
| SCHEMBL9818531 | 0.78 | ALDH1A1 (0.77) | KMT2ANPC1RAB9AMEN1ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5001157-A | Substituted N-[[2-(aminocarbonyl)phenylamino]thioxomethyl]benzamides | AMERICAN CYANAMID COMPANY (US) | 1991-03-19 | — | — | US | claimed |
| US-5084457-A | Cognition activators and nervous system disorders | AMERICAN CYANAMID COMPANY (US) | 1992-01-28 | — | — | US | disclosed |
| US-5001157-A | Substituted N-[[2-(aminocarbonyl)phenylamino]thioxomethyl]benzamides | AMERICAN CYANAMID COMPANY (US) | 1991-03-19 | — | — | US | disclosed |