Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 12/20 | 0.80 |
| ▸ | KDM4E | B2RXH2 | 9/20 | 0.80 |
| ▸ | POLB | P06746 | 2/20 | 0.80 |
| ▸ | ALOX12 | P18054 | 6/20 | 0.65 |
| ▸ | MAPT | P10636 | 5/20 | 0.65 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.65 |
| ▸ | SMN1; SMN2 | Q16637 | 6/20 | 0.60 |
| ▸ | LMNA | P02545 | 4/20 | 0.60 |
| ▸ | HPGD | P15428 | 3/20 | 0.58 |
| ▸ | NPC1 | O15118 | 3/20 | 0.58 |
| ▸ | RAB9A | P51151 | 3/20 | 0.58 |
| ▸ | STAT1 | P42224 | 1/20 | 0.58 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.56 |
| ▸ | MEN1 | O00255 | 2/20 | 0.56 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.54 |
| ▸ | HTT | P42858 | 2/20 | 0.54 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.54 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.54 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.53 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.52 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9728569 | 0.86 | ALDH1A1 (0.74) | ALDH1A1KDM4EPOLBALOX12MAPT | |
| SCHEMBL9728074 | 0.85 | ALDH1A1 (0.70) | ALDH1A1KDM4EPOLBALOX12MAPT | |
| SCHEMBL9728096 | 0.84 | EPHX1 (0.66) | ALDH1A1KDM4EPOLBALOX12MAPT | |
| SCHEMBL14096553 | 0.82 | ALDH1A1 (0.71) | ALDH1A1KDM4EPOLBALOX12MAPT | |
| SCHEMBL9818531 | 0.80 | ALDH1A1 (0.77) | ALDH1A1KDM4EPOLBALOX12MAPT | |
| SCHEMBL3054870 | 0.80 | ALDH1A1 (0.72) | ALDH1A1KDM4EPOLBALOX12MAPT | |
| SCHEMBL9818475 | 0.80 | LMNA (0.56) | ALDH1A1KDM4EPOLBALOX12MAPT | |
| SCHEMBL3717813 | 0.80 | ALDH1A1 (0.68) | ALDH1A1KDM4EPOLBALOX12MAPT | |
| SCHEMBL14096580 | 0.79 | ALDH1A1 (0.66) | ALDH1A1KDM4EPOLBALOX12MAPT | |
| SCHEMBL9729151 | 0.78 | KMT2A (0.61) | ALDH1A1KDM4EALOX12MAPTNPSR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5001157-A | Substituted N-[[2-(aminocarbonyl)phenylamino]thioxomethyl]benzamides | AMERICAN CYANAMID COMPANY (US) | 1991-03-19 | — | — | US | claimed |
| US-5084457-A | Cognition activators and nervous system disorders | AMERICAN CYANAMID COMPANY (US) | 1992-01-28 | — | — | US | disclosed |
| US-5001157-A | Substituted N-[[2-(aminocarbonyl)phenylamino]thioxomethyl]benzamides | AMERICAN CYANAMID COMPANY (US) | 1991-03-19 | — | — | US | disclosed |