Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 1/20 | 0.63 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.63 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.63 |
| ▸ | ALDH1A1 | P00352 | 9/20 | 0.59 |
| ▸ | HPGD | P15428 | 5/20 | 0.59 |
| ▸ | MAPT | P10636 | 4/20 | 0.59 |
| ▸ | GAA | P10253 | 1/20 | 0.59 |
| ▸ | APOBEC3G | Q9HC16 | 1/20 | 0.59 |
| ▸ | MGLL | Q99685 | 4/20 | 0.52 |
| ▸ | FAAH | O00519 | 3/20 | 0.52 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.51 |
| ▸ | PKM | P14618 | 1/20 | 0.47 |
| ▸ | HTT | P42858 | 1/20 | 0.46 |
| ▸ | AKR1C3 | P42330 | 1/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.45 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.45 |
| ▸ | TSHR | P16473 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21455291 | 0.76 | ALDH1A1 (0.71) | MEN1CYP2C19KMT2AALDH1A1HPGD | |
| SCHEMBL4394405 | 0.75 | ALDH1A1 (1.00) | MEN1CYP2C19KMT2AALDH1A1HPGD | |
| SCHEMBL3870989 | 0.74 | MEN1 (0.63) | MEN1CYP2C19KMT2AALDH1A1HPGD | |
| SCHEMBL26458283 | 0.74 | MGLL (0.54) | MEN1CYP2C19KMT2AALDH1A1HPGD | |
| SCHEMBL8742259 | 0.74 | KMT2A (0.79) | MEN1CYP2C19KMT2AALDH1A1HPGD | |
| SCHEMBL14712034 | 0.73 | KMT2A (0.58) | MEN1CYP2C19KMT2AALDH1A1HPGD | |
| SCHEMBL4109692 | 0.72 | NPSR1 (0.62) | KMT2AALDH1A1HPGDGAAPKM | |
| SCHEMBL11156037 | 0.71 | MEN1 (0.67) | MEN1CYP2C19KMT2AALDH1A1HPGD | |
| SCHEMBL1108678 | 0.71 | MGLL (0.82) | MEN1CYP2C19KMT2AALDH1A1HPGD | |
| SCHEMBL6177281 | 0.70 | ALDH1A1 (0.57) | MEN1CYP2C19KMT2AALDH1A1HPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5102667-A | Antiallergens, antiinflammatory agents, nervous system disorders, immunology, psychological disorders | RHONE-POULENC SANTE (FR) | 1992-04-07 | — | — | US | disclosed |