Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.42 |
| ▸ | SLC6A2 | P23975 | 3/20 | 0.41 |
| ▸ | SLC6A4 | P31645 | 3/20 | 0.41 |
| ▸ | LMNA | P02545 | 2/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.41 |
| ▸ | PPARG | P37231 | 1/20 | 0.40 |
| ▸ | PPARA | Q07869 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.39 |
| ▸ | CYP2A13 | Q16696 | 1/20 | 0.38 |
| ▸ | SLC6A3 | Q01959 | 2/20 | 0.37 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.37 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.37 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.37 |
| ▸ | ACHE | P22303 | 1/20 | 0.37 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.37 |
| ▸ | ADRA2B | P18089 | 1/20 | 0.37 |
| ▸ | ADRA2C | P18825 | 1/20 | 0.37 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6900865 | 0.87 | GABRA1 (0.38) | TAAR1SLC6A2SLC6A4KMT2ASLC6A3 | |
| SCHEMBL22361192 | 0.85 | TAAR1 (0.43) | TAAR1SLC6A2SLC6A4LMNAKDM4E | |
| SCHEMBL18658983 | 0.81 | TAAR1 (0.43) | TAAR1SLC6A2SLC6A4LMNAKDM4E | |
| SCHEMBL17580770 | 0.79 | PPARG (0.40) | TAAR1SLC6A2SLC6A4KDM4EPPARG | |
| SCHEMBL508570 | 0.78 | GABRA1 (0.54) | TAAR1SLC6A2SLC6A4PPARGPPARA | |
| SCHEMBL29560806 | 0.78 | GABRA1 (0.54) | TAAR1SLC6A2SLC6A4PPARGPPARA | |
| SCHEMBL5499384 | 0.78 | GABRA1 (0.54) | TAAR1SLC6A2SLC6A4PPARGPPARA | |
| SCHEMBL6205188 | 0.78 | LMNA (0.43) | TAAR1SLC6A2SLC6A4LMNAKDM4E | |
| SCHEMBL6205184 | 0.78 | LMNA (0.43) | TAAR1SLC6A2SLC6A4LMNAKDM4E | |
| SCHEMBL1840025 | 0.78 | HSPA5 (0.46) | TAAR1SLC6A2SLC6A4SLC6A3CYP3A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5171354-A | Herbicides | CIBA-GEIGY CORPORATION (US) | 1992-12-15 | — | — | US | disclosed |