Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC6A4 | P31645 | 3/20 | 0.40 |
| ▸ | SLC6A3 | Q01959 | 3/20 | 0.40 |
| ▸ | MGLL | Q99685 | 1/20 | 0.39 |
| ▸ | HSD11B1 | P28845 | 2/20 | 0.37 |
| ▸ | SLC6A2 | P23975 | 2/20 | 0.37 |
| ▸ | CCR2 | P41597 | 1/20 | 0.36 |
| ▸ | DPP4 | P27487 | 3/20 | 0.36 |
| ▸ | DPP9 | Q86TI2 | 2/20 | 0.36 |
| ▸ | DPP8 | Q6V1X1 | 1/20 | 0.36 |
| ▸ | KCNA3 | P22001 | 1/20 | 0.35 |
| ▸ | CCR1 | P32246 | 1/20 | 0.34 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.34 |
| ▸ | HTR2C | P28335 | 2/20 | 0.34 |
| ▸ | HTR2A | P28223 | 1/20 | 0.34 |
| ▸ | HTR2B | P41595 | 1/20 | 0.34 |
| ▸ | HCAR3 | P49019 | 1/20 | 0.34 |
| ▸ | HCAR2 | Q8TDS4 | 1/20 | 0.34 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9729483 | 0.81 | HDAC4 (0.40) | MGLLHSD11B1CCR2HTR2CHTR2A | |
| SCHEMBL9729634 | 0.81 | KDM1A (0.40) | SLC6A4SLC6A3MGLLHSD11B1SLC6A2 | |
| SCHEMBL744007 | 0.79 | MEN1 (0.44) | HSD11B1MEN1KMT2A | |
| SCHEMBL11465652 | 0.72 | HTR2A (0.54) | HTR2CHTR2AHTR2B | |
| SCHEMBL14531844 | 0.70 | PDE4B (0.48) | SLC6A4MEN1KMT2A | |
| SCHEMBL9729268 | 0.69 | MEN1 (0.60) | SLC6A4SLC6A3HSD11B1SLC6A2CCR2 | |
| SCHEMBL14260462 | 0.68 | OPRM1 (0.49) | KCNA3KMT2AALOX5 | |
| SCHEMBL11796632 | 0.67 | KCNA3 (0.48) | SLC6A4SLC6A3HSD11B1SLC6A2CCR2 | |
| SCHEMBL5876108 | 0.66 | POLB (0.43) | SLC6A4SLC6A3MGLLHSD11B1ALOX5 | |
| SCHEMBL27906398 | 0.65 | SLC6A4 (0.50) | SLC6A4SLC6A3HSD11B1SLC6A2CCR2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5112988-A | ISOINDOLONE DERIVATIVES | RHONE-POULENC SANTE (FR) | 1992-05-12 | — | — | US | disclosed |
| US-5102667-A | Antiallergens, antiinflammatory agents, nervous system disorders, immunology, psychological disorders | RHONE-POULENC SANTE (FR) | 1992-04-07 | — | — | US | disclosed |