Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 3/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.37 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.37 |
| ▸ | DPP4 | P27487 | 3/20 | 0.36 |
| ▸ | ANPEP | P15144 | 2/20 | 0.36 |
| ▸ | NR1H2 | P55055 | 1/20 | 0.35 |
| ▸ | NR1H3 | Q13133 | 1/20 | 0.35 |
| ▸ | GABRA1 | P14867 | 2/20 | 0.31 |
| ▸ | GABRG2 | P18507 | 2/20 | 0.31 |
| ▸ | GABRB3 | P28472 | 2/20 | 0.31 |
| ▸ | FAAH | O00519 | 1/20 | 0.30 |
| ▸ | CA1 | P00915 | 1/20 | 0.30 |
| ▸ | CA2 | P00918 | 1/20 | 0.30 |
| ▸ | LMNA | P02545 | 1/20 | 0.30 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.30 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.30 |
| ▸ | HPGD | P15428 | 1/20 | 0.30 |
| ▸ | GABRB1 | P18505 | 1/20 | 0.30 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.30 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9728711 | 0.93 | TSHR (0.46) | TSHRALDH1A1ALOX15DPP4ANPEP | |
| SCHEMBL9728430 | 0.90 | DPP4 (0.33) | TSHRALDH1A1ALOX15DPP4ANPEP | |
| SCHEMBL9728613 | 0.77 | GABRA1 (0.37) | TSHRALDH1A1GABRA1CA2CYP3A4 | |
| SCHEMBL9728180 | 0.74 | DPP4 (0.42) | TSHRALDH1A1ALOX15DPP4ANPEP | |
| SCHEMBL9728307 | 0.70 | TSHR (0.50) | TSHRALDH1A1ALOX15DPP4ANPEP | |
| SCHEMBL9728387 | 0.69 | DPP4 (0.36) | TSHRALDH1A1ALOX15DPP4ANPEP | |
| SCHEMBL9728918 | 0.69 | ALDH1A1 (0.46) | TSHRALDH1A1ALOX15DPP4ANPEP | |
| SCHEMBL9728241 | 0.68 | DPP4 (0.37) | TSHRALDH1A1ALOX15DPP4ANPEP | |
| SCHEMBL9728643 | 0.67 | DPP4 (0.39) | TSHRALDH1A1ALOX15DPP4ANPEP | |
| SCHEMBL9728513 | 0.66 | TSHR (0.36) | TSHRALDH1A1LMNAHPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0406163-A1 | Thioxotetrazolines | CIBA-GEIGY AG (CH) | 1991-01-02 | — | — | EP | claimed |
| US-5138068-A | Pesticide | CIBA-GEIGY CORPORATION (US) | 1992-08-11 | — | — | US | disclosed |
| US-5066667-A | Controlling insects and arachnids | CIBA-GEIGY CORPORATION (US) | 1991-11-19 | — | — | US | disclosed |
| EP-0406163-A1 | Thioxotetrazolines | CIBA-GEIGY AG (CH) | 1991-01-02 | — | — | EP | disclosed |