Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DPP4 | P27487 | 5/20 | 0.37 |
| ▸ | NR1H2 | P55055 | 1/20 | 0.37 |
| ▸ | NR1H3 | Q13133 | 1/20 | 0.37 |
| ▸ | ANPEP | P15144 | 5/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.34 |
| ▸ | TSHR | P16473 | 3/20 | 0.34 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.34 |
| ▸ | HTT | P42858 | 1/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.31 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.31 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.31 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.31 |
| ▸ | GLA | P06280 | 2/20 | 0.31 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.31 |
| ▸ | GAA | P10253 | 2/20 | 0.31 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.31 |
| ▸ | HPGD | P15428 | 2/20 | 0.31 |
| ▸ | TP53 | P04637 | 1/20 | 0.31 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.31 |
| ▸ | MAPT | P10636 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9728643 | 0.85 | DPP4 (0.39) | DPP4NR1H2NR1H3ANPEPALDH1A1 | |
| SCHEMBL9728430 | 0.81 | DPP4 (0.33) | DPP4NR1H2NR1H3ANPEPALDH1A1 | |
| SCHEMBL9729088 | 0.74 | CRHBP (0.34) | DPP4ANPEPALDH1A1KMT2ACYP1A2 | |
| SCHEMBL9728180 | 0.70 | DPP4 (0.42) | DPP4NR1H2NR1H3ANPEPALDH1A1 | |
| SCHEMBL9729305 | 0.68 | TSHR (0.37) | DPP4NR1H2NR1H3ANPEPALDH1A1 | |
| SCHEMBL8475825 | 0.68 | POLB (0.47) | DPP4NR1H2NR1H3ANPEPALDH1A1 | |
| SCHEMBL9728918 | 0.68 | ALDH1A1 (0.46) | DPP4NR1H2NR1H3ANPEPALDH1A1 | |
| SCHEMBL8526207 | 0.67 | DPP4 (0.38) | DPP4NR1H2NR1H3ANPEPALDH1A1 | |
| SCHEMBL16385896 | 0.66 | HTR1A (0.39) | DPP4NR1H2NR1H3ALDH1A1KMT2A | |
| SCHEMBL9728387 | 0.66 | DPP4 (0.36) | DPP4NR1H2NR1H3ANPEPALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5138068-A | Pesticide | CIBA-GEIGY CORPORATION (US) | 1992-08-11 | — | — | US | disclosed |
| US-5066667-A | Controlling insects and arachnids | CIBA-GEIGY CORPORATION (US) | 1991-11-19 | — | — | US | disclosed |