Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GRM2 | Q14416 | 4/20 | 0.33 |
| ▸ | GRM3 | Q14832 | 4/20 | 0.33 |
| ▸ | GRM8 | O00222 | 2/20 | 0.33 |
| ▸ | GRM4 | Q14833 | 1/20 | 0.33 |
| ▸ | GRM6 | O15303 | 3/20 | 0.33 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.32 |
| ▸ | POLB | P06746 | 1/20 | 0.32 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10396183 | 0.79 | GRM8 (0.32) | GRM2GRM3GRM8GRM6 | |
| SCHEMBL9729624 | 0.72 | ALDH1A1 (0.37) | — | |
| SCHEMBL9729630 | 0.72 | ALDH1A1 (0.37) | — | |
| SCHEMBL11467630 | 0.71 | POLB (0.34) | GRM2GRM3GRM8GRM4GRM6 | |
| SCHEMBL28764921 | 0.67 | ALDH1A1 (0.42) | GRM2GRM3GRM8GRM4GRM6 | |
| SCHEMBL3423128 | 0.67 | RAB9A (0.35) | TDP1POLB | |
| SCHEMBL14540470 | 0.67 | RAB9A (0.35) | TDP1POLB | |
| SCHEMBL4069733 | 0.67 | POLB (0.39) | GRM2GRM3GRM8GRM6TDP1 | |
| SCHEMBL3464997 | 0.67 | POLB (0.39) | GRM2GRM3GRM8GRM6TDP1 | |
| SCHEMBL16756317 | 0.67 | POLB (0.39) | GRM2GRM3GRM8GRM6TDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5102793-A | STEREOSPECIFIC KETO REDUCTION OF BICYCLOOCTANDIONE-CARBOXYLIC ACID ESTERS BY MICROORGANISMS | SCHERING AKTIENGESELLSCHAFT (DE) | 1992-04-07 | — | — | US | disclosed |