Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALOX5 | P09917 | 6/20 | 0.59 |
| ▸ | MAOB | P27338 | 8/20 | 0.53 |
| ▸ | MAOA | P21397 | 5/20 | 0.53 |
| ▸ | CA2 | P00918 | 3/20 | 0.48 |
| ▸ | CA12 | O43570 | 1/20 | 0.48 |
| ▸ | CA1 | P00915 | 1/20 | 0.48 |
| ▸ | CA9 | Q16790 | 1/20 | 0.48 |
| ▸ | NPC1 | O15118 | 2/20 | 0.45 |
| ▸ | RAB9A | P51151 | 2/20 | 0.45 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.45 |
| ▸ | HPGD | P15428 | 1/20 | 0.45 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.45 |
| ▸ | GRM5 | P41594 | 1/20 | 0.45 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.45 |
| ▸ | RELA | Q04206 | 1/20 | 0.45 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.45 |
| ▸ | CA5A | P35218 | 2/20 | 0.43 |
| ▸ | MEN1 | O00255 | 1/20 | 0.43 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9729572 | 0.87 | ALOX5 (0.60) | ALOX5MAOBMAOA | |
| SCHEMBL9729591 | 0.85 | ALOX5 (0.61) | ALOX5MAOBMAOANPC1RAB9A | |
| SCHEMBL10088470 | 0.83 | MAOB (0.49) | ALOX5MAOBMAOACA2NPC1 | |
| SCHEMBL9729708 | 0.82 | ALOX5 (0.54) | ALOX5MAOB | |
| SCHEMBL6092993 | 0.80 | ALOX5 (0.76) | ALOX5MAOBMAOACA2CA12 | |
| Formamide SCHEMBL9729701 | 0.78 | ALOX5 (0.62) | ALOX5MAOBMAOACA2CA12 | |
| SCHEMBL10088453 | 0.78 | NPC1 (0.54) | ALOX5MAOBMAOANPC1RAB9A | |
| SCHEMBL27651197 | 0.78 | ALOX5 (0.65) | ALOX5MAOBMAOACA2CA12 | |
| SCHEMBL7202221 | 0.78 | ALOX5 (0.56) | ALOX5MAOBCA2CA12CA1 | |
| SCHEMBL8627404 | 0.77 | MAOB (0.57) | ALOX5MAOBCA2CA12CA9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5155130-A | Lipoxygenase inhibitors | CIBA-GEIGY CORPORATION (US) | 1992-10-13 | — | — | US | disclosed |
| EP-0412939-A2 | Certain benzopyran and benzothiopyran derivatives | CIBA-GEIGY AG (CH) | 1991-02-13 | — | — | EP | disclosed |