Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALOX5 | P09917 | 3/20 | 0.61 |
| ▸ | MAOB | P27338 | 11/20 | 0.55 |
| ▸ | MAOA | P21397 | 5/20 | 0.55 |
| ▸ | MEN1 | O00255 | 1/20 | 0.44 |
| ▸ | NPC1 | O15118 | 1/20 | 0.44 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.44 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.44 |
| ▸ | PKM | P14618 | 1/20 | 0.44 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.44 |
| ▸ | RAB9A | P51151 | 1/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.44 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.44 |
| ▸ | AR | P10275 | 1/20 | 0.43 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10088900 | 0.91 | MAOB (0.55) | ALOX5MAOBMAOAMEN1NPC1 | |
| SCHEMBL9729518 | 0.85 | ALOX5 (0.59) | ALOX5MAOBMAOAMEN1NPC1 | |
| Formamide SCHEMBL9730285 | 0.81 | ALOX5 (0.67) | ALOX5MAOBMAOAMEN1NPC1 | |
| SCHEMBL28002706 | 0.80 | PTGS2 (0.47) | ALOX5MAOB | |
| SCHEMBL9729952 | 0.78 | ALOX5 (0.67) | ALOX5MAOBMAOAMEN1NPC1 | |
| SCHEMBL2326732 | 0.77 | SRD5A1 (0.42) | ALOX5MAOBMAOAAR | |
| SCHEMBL10088453 | 0.76 | NPC1 (0.54) | ALOX5MAOBMAOAMEN1NPC1 | |
| SCHEMBL10088917 | 0.76 | MAOA (0.39) | ALOX5MAOBMAOAAR | |
| SCHEMBL9730281 | 0.76 | ALOX5 (1.00) | ALOX5 | |
| SCHEMBL10089019 | 0.74 | AR (0.38) | ALOX5MAOBMAOAMEN1NPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5155130-A | Lipoxygenase inhibitors | CIBA-GEIGY CORPORATION (US) | 1992-10-13 | — | — | US | disclosed |
| EP-0412939-A2 | Certain benzopyran and benzothiopyran derivatives | CIBA-GEIGY AG (CH) | 1991-02-13 | — | — | EP | disclosed |