Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAOB | P27338 | 5/20 | 0.57 |
| ▸ | MTNR1A | P48039 | 2/20 | 0.52 |
| ▸ | ALOX5 | P09917 | 2/20 | 0.50 |
| ▸ | SHMT2 | P34897 | 1/20 | 0.49 |
| ▸ | NR1H4 | Q96RI1 | 2/20 | 0.48 |
| ▸ | PTGS1 | P23219 | 2/20 | 0.47 |
| ▸ | PTGS2 | P35354 | 2/20 | 0.47 |
| ▸ | MAPT | P10636 | 3/20 | 0.46 |
| ▸ | GAA | P10253 | 2/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.46 |
| ▸ | NPC1 | O15118 | 1/20 | 0.46 |
| ▸ | HPGD | P15428 | 1/20 | 0.46 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.46 |
| ▸ | RAB9A | P51151 | 1/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.46 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.46 |
| ▸ | MEN1 | O00255 | 1/20 | 0.46 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.46 |
| ▸ | HTT | P42858 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9729530 | 0.88 | ALOX5 (0.54) | MAOBMTNR1AALOX5SHMT2NR1H4 | |
| SCHEMBL31544361 | 0.88 | ALOX5 (0.54) | MAOBMTNR1AALOX5SHMT2NR1H4 | |
| SCHEMBL29381912 | 0.84 | MAOB (0.53) | MAOBMTNR1AALOX5SHMT2NR1H4 | |
| SCHEMBL9729708 | 0.81 | ALOX5 (0.54) | MAOBALOX5PTGS1PTGS2ALOX12 | |
| SCHEMBL10310537 | 0.80 | PTGS1 (0.46) | MAOBALOX5NR1H4PTGS1PTGS2 | |
| SCHEMBL7202221 | 0.80 | ALOX5 (0.56) | MAOBMTNR1AALOX5MAPTKDM4E | |
| SCHEMBL266611 | 0.78 | MTNR1A (0.53) | MAOBMTNR1AALOX5SHMT2NR1H4 | |
| SCHEMBL10088476 | 0.77 | PTGS1 (0.44) | MAOBALOX5NR1H4PTGS1PTGS2 | |
| SCHEMBL9729518 | 0.77 | ALOX5 (0.59) | MAOBALOX5ALDH1A1NPC1HPGD | |
| SCHEMBL9158923 | 0.77 | MAOB (0.64) | MAOBMTNR1AALOX5SHMT2NR1H4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5717106-A | THERMAL DYE TRANSFER IMAGING | EASTMAN KODAK COMPANY (US) | 1998-02-10 | — | — | US | disclosed |
| US-5712223-A | YELLOW DYES WITH IMPROVED EFFICIENCY | EASTMAN KODAK COMPANY (US) | 1998-01-27 | — | — | US | disclosed |
| US-5162540-A | Process for the production of (+) biotin | LONZA LTD. (CH) | 1992-11-10 | — | — | US | disclosed |
| US-5155130-A | Lipoxygenase inhibitors | CIBA-GEIGY CORPORATION (US) | 1992-10-13 | — | — | US | disclosed |
| EP-0412939-A2 | Certain benzopyran and benzothiopyran derivatives | CIBA-GEIGY AG (CH) | 1991-02-13 | — | — | EP | disclosed |