Known targets — ChEMBL curated mechanism
The experimentally established mechanism targets of Oxalic Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDPK1 | O15530 | 4/20 | 0.42 |
| ▸ | ATM | Q13315 | 1/20 | 0.42 |
| ▸ | AR | P10275 | 4/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.39 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.39 |
| ▸ | PABPC1 | P11940 | 1/20 | 0.39 |
| ▸ | MEN1 | O00255 | 2/20 | 0.38 |
| ▸ | TP53 | P04637 | 2/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.38 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.38 |
| ▸ | PTGDR2 | Q9Y5Y4 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9730125 | 0.96 | PDPK1 (0.39) | PDPK1ATMARKMT2AL3MBTL1 | |
| SCHEMBL9729574 | 0.81 | PDPK1 (0.39) | PDPK1ATMARKMT2AL3MBTL1 | |
| SCHEMBL10584394 | 0.71 | SHMT2 (0.47) | PDPK1ATMKMT2APTGDR2 | |
| SCHEMBL3379391 | 0.65 | SHMT2 (0.48) | PDPK1ATMKMT2AMEN1NPSR1 | |
| SCHEMBL14356330 | 0.64 | HPGD (0.48) | KMT2ATP53SMN1; SMN2PTGDR2 | |
| SCHEMBL11816804 | 0.64 | HSD17B10 (0.52) | ATMTP53SMN1; SMN2NPSR1 | |
| SCHEMBL11825241 | 0.63 | KDM4E (0.60) | KMT2AL3MBTL1MEN1TP53SMN1; SMN2 | |
| Oxalic Acid SCHEMBL9730818 | 0.63 | MAPT (0.49) | L3MBTL1SMN1; SMN2PTGDR2 | |
| SCHEMBL9709017 | 0.61 | KMT2A (0.39) | KMT2AMEN1 | |
| SCHEMBL10720384 | 0.61 | KMT2A (0.38) | KMT2AMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5106863-A | Antiulcer agents, gastrointestinal disorders | ORTHO PHARMACEUTICAL CORPORATION (US) | 1992-04-21 | — | — | US | claimed |
| US-5106863-A | Antiulcer agents, gastrointestinal disorders | ORTHO PHARMACEUTICAL CORPORATION (US) | 1992-04-21 | — | — | US | disclosed |