Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALOX5 | P09917 | 3/20 | 1.00 |
| ▸ | SMN1; SMN2 | Q16637 | 6/20 | 0.50 |
| ▸ | NPC1 | O15118 | 4/20 | 0.50 |
| ▸ | RAB9A | P51151 | 4/20 | 0.50 |
| ▸ | MAOB | P27338 | 4/20 | 0.50 |
| ▸ | NFKB1 | P19838 | 3/20 | 0.50 |
| ▸ | NFKB2 | Q00653 | 3/20 | 0.50 |
| ▸ | RELA | Q04206 | 3/20 | 0.50 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.50 |
| ▸ | MAOA | P21397 | 3/20 | 0.50 |
| ▸ | MAPT | P10636 | 3/20 | 0.50 |
| ▸ | MEN1 | O00255 | 2/20 | 0.50 |
| ▸ | CASP3 | P42574 | 1/20 | 0.50 |
| ▸ | SENP8 | Q96LD8 | 1/20 | 0.50 |
| ▸ | SENP7 | Q9BQF6 | 1/20 | 0.50 |
| ▸ | SENP6 | Q9GZR1 | 1/20 | 0.50 |
| ▸ | KDM4E | B2RXH2 | 6/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.48 |
| ▸ | HPGD | P15428 | 1/20 | 0.47 |
| ▸ | PKM | P14618 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9058393 | 0.80 | ALOX5 (0.67) | ALOX5SMN1; SMN2NPC1RAB9AMAOB | |
| SCHEMBL9729757 | 0.79 | ALOX5 (0.72) | ALOX5 | |
| SCHEMBL16397645 | 0.78 | ALOX5 (0.64) | ALOX5SMN1; SMN2NPC1RAB9AMAOB | |
| SCHEMBL212724 | 0.78 | ALOX5 (0.64) | ALOX5SMN1; SMN2NPC1RAB9AMAOB | |
| SCHEMBL9729918 | 0.77 | ALOX5 (1.00) | ALOX5SMN1; SMN2NPC1RAB9AMAOB | |
| Hydrochloric Acid SCHEMBL23532714 | 0.77 | ALOX5 (0.62) | ALOX5SMN1; SMN2NPC1RAB9AMAOB | |
| SCHEMBL2154729 | 0.77 | ALOX5 (0.62) | ALOX5SMN1; SMN2NPC1RAB9AMAOB | |
| SCHEMBL31560392 | 0.77 | ALOX5 (0.62) | ALOX5SMN1; SMN2NPC1RAB9AMAOB | |
| Hydrochloric Acid SCHEMBL5770308 | 0.77 | ALOX5 (0.62) | ALOX5SMN1; SMN2NPC1RAB9AMAOB | |
| SCHEMBL545827 | 0.77 | ALOX5 (0.62) | ALOX5SMN1; SMN2NPC1RAB9AMAOB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5155130-A | Lipoxygenase inhibitors | CIBA-GEIGY CORPORATION (US) | 1992-10-13 | — | — | US | disclosed |
| EP-0412939-A2 | Certain benzopyran and benzothiopyran derivatives | CIBA-GEIGY AG (CH) | 1991-02-13 | — | — | EP | disclosed |