Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALOX5 | P09917 | 4/20 | 1.00 |
| ▸ | NR1H4 | Q96RI1 | 2/20 | 0.60 |
| ▸ | CA12 | O43570 | 2/20 | 0.52 |
| ▸ | CA9 | Q16790 | 2/20 | 0.52 |
| ▸ | MAOB | P27338 | 2/20 | 0.47 |
| ▸ | SHMT2 | P34897 | 1/20 | 0.47 |
| ▸ | NFKB1 | P19838 | 2/20 | 0.47 |
| ▸ | NFKB2 | Q00653 | 2/20 | 0.47 |
| ▸ | RELA | Q04206 | 2/20 | 0.47 |
| ▸ | NPC1 | O15118 | 2/20 | 0.47 |
| ▸ | RAB9A | P51151 | 2/20 | 0.47 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.44 |
| ▸ | MAPT | P10636 | 3/20 | 0.44 |
| ▸ | GAA | P10253 | 2/20 | 0.44 |
| ▸ | MEN1 | O00255 | 1/20 | 0.44 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.44 |
| ▸ | HTT | P42858 | 1/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.44 |
| ▸ | CA2 | P00918 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL432850 | 0.83 | ALOX5 (0.71) | ALOX5NR1H4CA12CA9MAOB | |
| SCHEMBL10470600 | 0.83 | ALOX5 (0.71) | ALOX5NR1H4CA12CA9MAOB | |
| SCHEMBL9729599 | 0.77 | ALOX5 (1.00) | ALOX5CA12CA9MAOBNFKB1 | |
| SCHEMBL22059556 | 0.76 | ALOX5 (0.61) | ALOX5NR1H4CA12CA9MAOB | |
| SCHEMBL5508253 | 0.75 | ALOX5 (0.60) | ALOX5NR1H4CA12CA9MAOB | |
| SCHEMBL9729757 | 0.75 | ALOX5 (0.72) | ALOX5ALOX12 | |
| SCHEMBL3128348 | 0.75 | NR1H4 (0.61) | ALOX5NR1H4CA12CA9SHMT2 | |
| SCHEMBL10470595 | 0.74 | ALOX5 (0.59) | ALOX5NR1H4CA12CA9MAOB | |
| SCHEMBL10470596 | 0.74 | ALOX5 (0.59) | ALOX5NR1H4CA12CA9MAOB | |
| SCHEMBL30572528 | 0.74 | NPC1 (0.69) | ALOX5NR1H4CA12CA9MAOB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5155130-A | Lipoxygenase inhibitors | CIBA-GEIGY CORPORATION (US) | 1992-10-13 | — | — | US | disclosed |
| EP-0412939-A2 | Certain benzopyran and benzothiopyran derivatives | CIBA-GEIGY AG (CH) | 1991-02-13 | — | — | EP | disclosed |