Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTT | P42858 | 3/20 | 0.50 |
| ▸ | IDO1 | P14902 | 3/20 | 0.47 |
| ▸ | RECQL | P46063 | 1/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.47 |
| ▸ | GAA | P10253 | 1/20 | 0.47 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.46 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.46 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.46 |
| ▸ | HDAC7 | Q8WUI4 | 1/20 | 0.46 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.46 |
| ▸ | HDAC10 | Q969S8 | 1/20 | 0.46 |
| ▸ | HDAC11 | Q96DB2 | 1/20 | 0.46 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.46 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.46 |
| ▸ | HDAC9 | Q9UKV0 | 1/20 | 0.46 |
| ▸ | HDAC5 | Q9UQL6 | 1/20 | 0.46 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.46 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.46 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.46 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9730240 | 0.82 | ERCC1 (0.40) | HTTALDH1A1GAAMEN1KMT2A | |
| SCHEMBL435206 | 0.80 | IDO1 (0.54) | HTTIDO1ALDH1A1GAACYP1A2 | |
| SCHEMBL837451 | 0.80 | ALDH1A1 (0.56) | HTTRECQLALDH1A1GAAHDAC3 | |
| SCHEMBL1525623 | 0.79 | ALDH1A1 (0.54) | HTTRECQLALDH1A1GAAHDAC3 | |
| SCHEMBL7641294 | 0.77 | GAA (0.50) | HTTRECQLALDH1A1GAAHDAC3 | |
| SCHEMBL12082232 | 0.77 | HDAC3 (0.52) | HTTIDO1RECQLALDH1A1GAA | |
| SCHEMBL2367026 | 0.77 | HDAC3 (0.52) | HTTIDO1RECQLALDH1A1GAA | |
| SCHEMBL11502956 | 0.77 | IDO1 (0.50) | HTTIDO1GAACYP1A2CYP3A4 | |
| SCHEMBL5000353 | 0.77 | IDO1 (0.51) | HTTIDO1CYP1A2CYP3A4CYP2C9 | |
| SCHEMBL29712851 | 0.77 | IDO1 (0.50) | IDO1GAACYP1A2CYP3A4CYP2C9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5171354-A | Herbicides | CIBA-GEIGY CORPORATION (US) | 1992-12-15 | — | — | US | disclosed |