Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KIF11 | P52732 | 1/20 | 0.46 |
| ▸ | MEN1 | O00255 | 3/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.46 |
| ▸ | P2RY1 | P47900 | 1/20 | 0.43 |
| ▸ | HTT | P42858 | 2/20 | 0.43 |
| ▸ | NPC1 | O15118 | 1/20 | 0.43 |
| ▸ | RAB9A | P51151 | 1/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.43 |
| ▸ | CYP1A2 | P05177 | 3/20 | 0.42 |
| ▸ | CYP2C19 | P33261 | 3/20 | 0.42 |
| ▸ | NPSR1 | Q6W5P4 | 3/20 | 0.42 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.42 |
| ▸ | GAA | P10253 | 2/20 | 0.42 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.42 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.42 |
| ▸ | HPGD | P15428 | 1/20 | 0.42 |
| ▸ | NTRK1 | P04629 | 2/20 | 0.42 |
| ▸ | POLB | P06746 | 1/20 | 0.41 |
| ▸ | NTRK2 | Q16620 | 1/20 | 0.41 |
| ▸ | LMNA | P02545 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9729542 | 0.90 | RAB9A (0.41) | KIF11MEN1KMT2AHTTNPC1 | |
| SCHEMBL29608194 | 0.89 | MEN1 (0.54) | KIF11MEN1KMT2AP2RY1CYP1A2 | |
| SCHEMBL352658 | 0.89 | MEN1 (0.54) | KIF11MEN1KMT2AP2RY1CYP1A2 | |
| SCHEMBL9728475 | 0.87 | MEN1 (0.39) | KIF11MEN1KMT2AHTTNPC1 | |
| SCHEMBL10338942 | 0.83 | BRAF (0.46) | MEN1KMT2AP2RY1 | |
| SCHEMBL9743981 | 0.80 | MEN1 (0.43) | MEN1KMT2ACYP1A2CYP2C19NPSR1 | |
| SCHEMBL9727936 | 0.80 | KMT2A (0.40) | MEN1KMT2AP2RY1HTTNPC1 | |
| SCHEMBL9728803 | 0.79 | MEN1 (0.52) | KIF11MEN1KMT2AHTTNPC1 | |
| SCHEMBL10606310 | 0.79 | MEN1 (0.52) | MEN1KMT2ANPC1RAB9ACYP1A2 | |
| SCHEMBL10647027 | 0.79 | PYGL (0.61) | NPC1RAB9ANTRK1TRPV1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0246061-B1 | A BENZOYLUREA DERIVATIVE AND ITS PRODUCTION AND USE | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 1992-03-18 | — | — | EP | disclosed |