Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 3/20 | 0.59 |
| ▸ | TP53 | P04637 | 2/20 | 0.59 |
| ▸ | HTT | P42858 | 1/20 | 0.59 |
| ▸ | MEN1 | O00255 | 2/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.39 |
| ▸ | GAA | P10253 | 1/20 | 0.39 |
| ▸ | TSHR | P16473 | 3/20 | 0.39 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.39 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.39 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.39 |
| ▸ | IDO1 | P14902 | 1/20 | 0.39 |
| ▸ | TDO2 | P48775 | 1/20 | 0.39 |
| ▸ | PYCR1 | P32322 | 1/20 | 0.39 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.37 |
| ▸ | MAPT | P10636 | 2/20 | 0.36 |
| ▸ | POLB | P06746 | 2/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6141121 | 0.82 | LMNA (0.57) | LMNATP53HTTMEN1KMT2A | |
| SCHEMBL10079577 | 0.80 | PYCR1 (0.41) | LMNATP53HTTMEN1KMT2A | |
| SCHEMBL254284 | 0.78 | LMNA (0.68) | LMNATP53HTTMEN1KMT2A | |
| SCHEMBL31045502 | 0.78 | LMNA (0.68) | LMNATP53HTTMEN1KMT2A | |
| SCHEMBL18097894 | 0.78 | TP53 (0.68) | LMNATP53HTTMEN1KMT2A | |
| SCHEMBL609775 | 0.78 | TP53 (0.47) | LMNATP53HTTALDH1A1GAA | |
| SCHEMBL28351852 | 0.78 | TP53 (0.57) | LMNATP53HTTMEN1KMT2A | |
| SCHEMBL18075310 | 0.76 | PDE2A (0.65) | LMNA | |
| SCHEMBL15053379 | 0.76 | TP53 (0.65) | LMNATP53HTTMEN1KMT2A | |
| SCHEMBL5108877 | 0.76 | TP53 (0.65) | LMNATP53HTTMEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5171354-A | Herbicides | CIBA-GEIGY CORPORATION (US) | 1992-12-15 | — | — | US | disclosed |