Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALOX5 | P09917 | 6/20 | 0.59 |
| ▸ | AKR1C4 | P17516 | 1/20 | 0.48 |
| ▸ | AKR1C3 | P42330 | 1/20 | 0.48 |
| ▸ | AKR1C2 | P52895 | 1/20 | 0.48 |
| ▸ | AKR1C1 | Q04828 | 1/20 | 0.48 |
| ▸ | LMNA | P02545 | 2/20 | 0.44 |
| ▸ | TP53 | P04637 | 2/20 | 0.44 |
| ▸ | FAAH | O00519 | 2/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9730306 | 0.76 | ALOX5 (0.80) | ALOX5 | |
| SCHEMBL9729641 | 0.74 | ALOX5 (1.00) | ALOX5 | |
| SCHEMBL28379701 | 0.72 | TP53 (0.63) | LMNATP53 | |
| SCHEMBL22165412 | 0.72 | TP53 (0.63) | LMNATP53 | |
| SCHEMBL30292011 | 0.72 | TP53 (0.63) | LMNATP53 | |
| SCHEMBL1519082 | 0.72 | TP53 (0.63) | LMNATP53 | |
| SCHEMBL8641892 | 0.70 | ALOX5 (0.42) | ALOX5FAAH | |
| SCHEMBL1519402 | 0.70 | TP53 (0.49) | AKR1C4AKR1C3AKR1C2AKR1C1LMNA | |
| SCHEMBL16303419 | 0.70 | MTNR1A (0.66) | LMNATP53 | |
| SCHEMBL1519543 | 0.69 | AKR1C4 (0.59) | AKR1C4AKR1C3AKR1C2AKR1C1LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5155130-A | Lipoxygenase inhibitors | CIBA-GEIGY CORPORATION (US) | 1992-10-13 | — | — | US | disclosed |
| EP-0412939-A2 | Certain benzopyran and benzothiopyran derivatives | CIBA-GEIGY AG (CH) | 1991-02-13 | — | — | EP | disclosed |