Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HNF4A | P41235 | 1/20 | 0.47 |
| ▸ | DHODH | Q02127 | 3/20 | 0.44 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.44 |
| ▸ | CYP2C8 | P10632 | 1/20 | 0.44 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.44 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.43 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.43 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.43 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.42 |
| ▸ | MEN1 | O00255 | 2/20 | 0.42 |
| ▸ | MAPT | P10636 | 2/20 | 0.42 |
| ▸ | HTT | P42858 | 1/20 | 0.42 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.42 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.42 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.42 |
| ▸ | PDE10A | Q9Y233 | 1/20 | 0.41 |
| ▸ | CHRNB2 | P17787 | 3/20 | 0.41 |
| ▸ | CHRNA4 | P43681 | 3/20 | 0.41 |
| ▸ | CHRNB4 | P30926 | 2/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28085880 | 0.76 | ALDH1A1 (0.46) | HNF4ADHODHCYP3A4CYP2C8CYP2C9 | |
| SCHEMBL9153622 | 0.73 | MAPT (0.39) | HNF4ADHODHCYP3A4HDAC4HDAC2 | |
| SCHEMBL28288595 | 0.71 | LMNA (0.47) | HNF4ADHODHCYP3A4CYP2C8CYP2C9 | |
| SCHEMBL3082243 | 0.70 | FOLH1 (0.45) | HNF4ADHODHCYP3A4CYP2C8CYP2C9 | |
| SCHEMBL10476973 | 0.70 | DHODH (0.54) | DHODHCYP3A4CYP2C8CYP2C9KMT2A | |
| Bicarbonate SCHEMBL27850284 | 0.70 | HDAC8 (0.61) | CYP2C9HDAC8HDAC6KMT2AMEN1 | |
| SCHEMBL4856686 | 0.69 | MEN1 (0.49) | HDAC8HDAC6KMT2AMEN1MAPT | |
| SCHEMBL27918049 | 0.69 | CA12 (0.54) | DHODHCYP3A4CYP2C8CYP2C9KMT2A | |
| SCHEMBL24696780 | 0.69 | MCL1 (0.49) | HNF4ACYP2C9HDAC4HDAC2HDAC8 | |
| SCHEMBL9245987 | 0.68 | HNF4A (0.78) | HNF4ACYP3A4CYP2C9HDAC4HDAC2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5162510-A | Prepared by condensing phenolic compounds with a 1,2-naphthoquinonediazide-4-sulfonic acid halide and an organic acid halide | HOECHST CELANESE CORPORATION (US) | 1992-11-10 | — | — | US | claimed |