Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP3A4 | P08684 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.35 |
| ▸ | TSHR | P16473 | 1/20 | 0.35 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.35 |
| ▸ | MEN1 | O00255 | 3/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.34 |
| ▸ | NPC1 | O15118 | 2/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.34 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.34 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.34 |
| ▸ | RHOA | P61586 | 1/20 | 0.34 |
| ▸ | LMNA | P02545 | 2/20 | 0.33 |
| ▸ | TP53 | P04637 | 1/20 | 0.33 |
| ▸ | HPGD | P15428 | 1/20 | 0.33 |
| ▸ | RAB9A | P51151 | 1/20 | 0.33 |
| ▸ | SREBF1 | P36956 | 5/20 | 0.33 |
| ▸ | NR1H3 | Q13133 | 5/20 | 0.33 |
| ▸ | SNCA | P37840 | 1/20 | 0.33 |
| ▸ | APP | P05067 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9729481 | 0.78 | ALDH1A1 (0.48) | CYP3A4ALDH1A1TSHRHSD17B10MEN1 | |
| SCHEMBL3016567 | 0.76 | MAPT (0.40) | ALDH1A1TSHRHSD17B10MEN1KMT2A | |
| SCHEMBL9729949 | 0.76 | CYP3A4 (0.44) | CYP3A4ALDH1A1TSHRHSD17B10MEN1 | |
| SCHEMBL10591189 | 0.73 | DAO (0.44) | CYP3A4TSHRMEN1KMT2ARXFP1 | |
| SCHEMBL29225979 | 0.65 | CYP3A4 (0.61) | CYP3A4ALDH1A1TSHRHSD17B10MEN1 | |
| SCHEMBL30933424 | 0.65 | CYP3A4 (0.61) | CYP3A4ALDH1A1TSHRHSD17B10MEN1 | |
| SCHEMBL4787535 | 0.65 | CYP3A4 (0.47) | CYP3A4ALDH1A1TSHRHSD17B10MEN1 | |
| SCHEMBL460642 | 0.65 | CYP3A4 (0.47) | CYP3A4ALDH1A1TSHRHSD17B10MEN1 | |
| SCHEMBL209680 | 0.64 | CYP3A4 (0.70) | CYP3A4ALDH1A1TSHRHSD17B10MEN1 | |
| SCHEMBL254063 | 0.64 | CYP3A4 (0.59) | CYP3A4ALDH1A1TSHRHSD17B10MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5138072-A | Process for the preparation of 5-chloro-3-chlorosulphonyl-2-thiophenecarboxylic acid esters | HAFSLUND NYCOMED PHARMA AKTIENGESELLSCHAFT (AT) | 1992-08-11 | — | — | US | disclosed |