Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP3A4 | P08684 | 1/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.39 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.39 |
| ▸ | TSHR | P16473 | 1/20 | 0.39 |
| ▸ | MAPT | P10636 | 5/20 | 0.39 |
| ▸ | MEN1 | O00255 | 2/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.39 |
| ▸ | RHOA | P61586 | 1/20 | 0.37 |
| ▸ | TP53 | P04637 | 3/20 | 0.36 |
| ▸ | SNCA | P37840 | 1/20 | 0.36 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.35 |
| ▸ | NPC1 | O15118 | 2/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.35 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.35 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.35 |
| ▸ | LMNA | P02545 | 4/20 | 0.35 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.34 |
| ▸ | HPGD | P15428 | 2/20 | 0.34 |
| ▸ | GAA | P10253 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8973307 | 0.81 | PKM (0.45) | CYP3A4ALDH1A1TSHRMAPTMEN1 | |
| SCHEMBL18984964 | 0.77 | CYP3A4 (0.59) | CYP3A4ALDH1A1HSD17B10TSHRMAPT | |
| SCHEMBL9729920 | 0.76 | CYP3A4 (0.40) | CYP3A4ALDH1A1HSD17B10TSHRMAPT | |
| SCHEMBL4786272 | 0.76 | ALDH1A1 (0.54) | CYP3A4ALDH1A1HSD17B10TSHRMAPT | |
| SCHEMBL388034 | 0.75 | MAPT (0.55) | TSHRMAPTMEN1KMT2ATP53 | |
| SCHEMBL9728565 | 0.71 | LMNA (0.62) | CYP3A4TSHRMEN1KMT2AKDM4E | |
| SCHEMBL9433064 | 0.71 | LMNA (0.44) | CYP3A4TSHRMAPTMEN1KMT2A | |
| SCHEMBL5483086 | 0.70 | HPGD (0.48) | CYP3A4ALDH1A1MAPTMEN1KMT2A | |
| SCHEMBL11043471 | 0.69 | CYP3A4 (0.56) | CYP3A4ALDH1A1HSD17B10TSHRMAPT | |
| SCHEMBL27256323 | 0.69 | KMT2A (0.46) | CYP3A4ALDH1A1TSHRMAPTMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| JP-1313474-A | — | — | None | — | — | JP | disclosed |
| US-5156944-A | LIGHT-SENSITIVE SILVER HALIDE COLOR PHOTOGRAPHIC MATERIAL HAVING CROSS-EMULSION SENSITIVE DIR COMPOUNDS | KONICA CORPORATION (JP) | 1992-10-20 | — | — | US | disclosed |
| US-5138072-A | Process for the preparation of 5-chloro-3-chlorosulphonyl-2-thiophenecarboxylic acid esters | HAFSLUND NYCOMED PHARMA AKTIENGESELLSCHAFT (AT) | 1992-08-11 | — | — | US | disclosed |
| JP-H01313474-A | PRODUCTION OF 5-CHLORO-3-CHLOROSULFONYL-2-THIOPHENECARBOXYLIC ESTER | CL PHARMA AG | 1989-12-18 | — | — | JP | disclosed |
| US-H504-H | DIAZOTIZATION OF AMINE, SULFONATION | E. I. DU PONT DE NEMOURS (US) | 1988-08-02 | — | — | US | disclosed |
| US-H504-H | DIAZOTIZATION OF AMINE, SULFONATION | E. I. DU PONT DE NEMOURS (US) | 1988-08-02 | — | — | US | disclosed |
| US-4725529-A | Developing inhibitor arrangment in light-sensitive silver halide color photographic materials | KONISHIROKU PHOTO INDUSTRY CO., LTD. (JP) | 1988-02-16 | — | — | US | disclosed |