Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.48 |
| ▸ | HSD17B10 | Q99714 | 4/20 | 0.48 |
| ▸ | TSHR | P16473 | 1/20 | 0.48 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 8/20 | 0.39 |
| ▸ | NPC1 | O15118 | 7/20 | 0.39 |
| ▸ | MAPT | P10636 | 6/20 | 0.39 |
| ▸ | RAB9A | P51151 | 6/20 | 0.39 |
| ▸ | MEN1 | O00255 | 5/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 5/20 | 0.39 |
| ▸ | HPGD | P15428 | 4/20 | 0.39 |
| ▸ | TP53 | P04637 | 3/20 | 0.37 |
| ▸ | CASP3 | P42574 | 2/20 | 0.37 |
| ▸ | SENP8 | Q96LD8 | 2/20 | 0.37 |
| ▸ | SENP7 | Q9BQF6 | 2/20 | 0.37 |
| ▸ | SENP6 | Q9GZR1 | 2/20 | 0.37 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.37 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.37 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9729920 | 0.78 | CYP3A4 (0.40) | ALDH1A1HSD17B10TSHRCYP3A4KDM4E | |
| SCHEMBL3244461 | 0.78 | ALDH1A1 (0.44) | ALDH1A1HSD17B10TSHRCYP3A4KDM4E | |
| SCHEMBL9683184 | 0.73 | ALDH1A1 (0.51) | ALDH1A1HSD17B10TSHRCYP3A4KDM4E | |
| Hydrochloric Acid SCHEMBL31120455 | 0.72 | KDM4E (0.59) | ALDH1A1HSD17B10TSHRKDM4ENPC1 | |
| SCHEMBL4786272 | 0.72 | ALDH1A1 (0.54) | ALDH1A1HSD17B10TSHRCYP3A4KDM4E | |
| SCHEMBL7752080 | 0.70 | ALDH1A1 (0.63) | ALDH1A1HSD17B10TSHRCYP3A4KDM4E | |
| SCHEMBL5102380 | 0.70 | KDM4E (0.54) | ALDH1A1HSD17B10TSHRCYP3A4KDM4E | |
| SCHEMBL8788657 | 0.70 | ALDH1A1 (0.63) | ALDH1A1HSD17B10TSHRCYP3A4KDM4E | |
| SCHEMBL12247521 | 0.69 | IKBKB (0.56) | ALDH1A1TSHRCYP3A4KDM4ENPC1 | |
| SCHEMBL4787535 | 0.68 | CYP3A4 (0.47) | ALDH1A1HSD17B10TSHRCYP3A4KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5138072-A | Process for the preparation of 5-chloro-3-chlorosulphonyl-2-thiophenecarboxylic acid esters | HAFSLUND NYCOMED PHARMA AKTIENGESELLSCHAFT (AT) | 1992-08-11 | — | — | US | disclosed |