Known targets — ChEMBL curated mechanism
The experimentally established mechanism targets of Oxalic Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MTNR1A | P48039 | 4/20 | 0.52 |
| ▸ | MTNR1B | P49286 | 3/20 | 0.52 |
| ▸ | TBXA2R | P21731 | 1/20 | 0.43 |
| ▸ | TRPV1 | Q8NER1 | 1/20 | 0.43 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.40 |
| ▸ | HPGD | P15428 | 1/20 | 0.40 |
| ▸ | HTT | P42858 | 1/20 | 0.40 |
| ▸ | MAPK10 | P53779 | 1/20 | 0.40 |
| ▸ | NCOA1 | Q15788 | 1/20 | 0.40 |
| ▸ | NCOA3 | Q9Y6Q9 | 1/20 | 0.40 |
| ▸ | CDYL2 | Q8N8U2 | 1/20 | 0.39 |
| ▸ | CDYL | Q9Y232 | 1/20 | 0.39 |
| ▸ | CDY1; CDY1B | Q9Y6F8 | 1/20 | 0.39 |
| ▸ | PPARG | P37231 | 1/20 | 0.39 |
| ▸ | PPARA | Q07869 | 1/20 | 0.39 |
| ▸ | MAOB | P27338 | 2/20 | 0.38 |
| ▸ | MAOA | P21397 | 1/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.38 |
| ▸ | POLB | P06746 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9729569 | 0.95 | MTNR1A (0.51) | MTNR1AMTNR1BTBXA2RTRPV1MAPK1 | |
| SCHEMBL9501822 | 0.76 | TDP1 (0.47) | MAPK1HTTKDM4E | |
| SCHEMBL9730522 | 0.76 | TDP1 (0.47) | MAPK1HTTKDM4E | |
| SCHEMBL9501830 | 0.76 | TDP1 (0.47) | MAPK1HTTKDM4E | |
| SCHEMBL7128052 | 0.72 | MTNR1A (0.54) | MTNR1AMTNR1BTBXA2RMAPK1ALDH1A1 | |
| SCHEMBL10643013 | 0.69 | TDP1 (0.55) | TRPV1ALDH1A1HTTPPARGPPARA | |
| SCHEMBL10643016 | 0.69 | TDP1 (0.55) | TRPV1ALDH1A1HTTPPARGPPARA | |
| SCHEMBL10603795 | 0.69 | MTNR1A (0.59) | MTNR1AMTNR1BMAPK1ALDH1A1HPGD | |
| SCHEMBL9190336 | 0.69 | MTNR1A (1.00) | MTNR1AMTNR1B | |
| SCHEMBL29962224 | 0.69 | MTNR1A (1.00) | MTNR1AMTNR1B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5106863-A | Antiulcer agents, gastrointestinal disorders | ORTHO PHARMACEUTICAL CORPORATION (US) | 1992-04-21 | — | — | US | disclosed |