Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MTNR1A | P48039 | 2/20 | 0.51 |
| ▸ | MTNR1B | P49286 | 1/20 | 0.51 |
| ▸ | PPARG | P37231 | 1/20 | 0.42 |
| ▸ | PPARA | Q07869 | 1/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.41 |
| ▸ | HPGD | P15428 | 2/20 | 0.41 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.41 |
| ▸ | HTT | P42858 | 1/20 | 0.41 |
| ▸ | MAPK10 | P53779 | 1/20 | 0.41 |
| ▸ | NCOA1 | Q15788 | 1/20 | 0.41 |
| ▸ | NCOA3 | Q9Y6Q9 | 1/20 | 0.41 |
| ▸ | TRPV1 | Q8NER1 | 1/20 | 0.41 |
| ▸ | TBXA2R | P21731 | 1/20 | 0.41 |
| ▸ | OPRD1 | P41143 | 1/20 | 0.39 |
| ▸ | BCHE | P06276 | 1/20 | 0.39 |
| ▸ | CDYL2 | Q8N8U2 | 1/20 | 0.38 |
| ▸ | CDYL | Q9Y232 | 1/20 | 0.38 |
| ▸ | CDY1; CDY1B | Q9Y6F8 | 1/20 | 0.38 |
| ▸ | ALOX15 | P16050 | 4/20 | 0.37 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Oxalic Acid SCHEMBL9729957 | 0.95 | MTNR1A (0.52) | MTNR1AMTNR1BPPARGPPARAALDH1A1 | |
| SCHEMBL9730522 | 0.80 | TDP1 (0.47) | MAPK1HTTTDP1KDM4E | |
| SCHEMBL9501822 | 0.80 | TDP1 (0.47) | MAPK1HTTTDP1KDM4E | |
| SCHEMBL9501830 | 0.80 | TDP1 (0.47) | MAPK1HTTTDP1KDM4E | |
| SCHEMBL7128052 | 0.76 | MTNR1A (0.54) | MTNR1AMTNR1BALDH1A1HPGDMAPK1 | |
| SCHEMBL10643013 | 0.73 | TDP1 (0.55) | PPARGPPARAALDH1A1HTTTRPV1 | |
| SCHEMBL10643016 | 0.73 | TDP1 (0.55) | PPARGPPARAALDH1A1HTTTRPV1 | |
| SCHEMBL10603795 | 0.72 | MTNR1A (0.59) | MTNR1AMTNR1BALDH1A1HPGDMAPK1 | |
| SCHEMBL12479232 | 0.72 | MTNR1A (0.66) | MTNR1AMTNR1BALDH1A1HPGDMAPK1 | |
| Bromide SCHEMBL29624933 | 0.71 | MTNR1A (0.58) | MTNR1AMTNR1BALDH1A1HPGDMAPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5106863-A | Antiulcer agents, gastrointestinal disorders | ORTHO PHARMACEUTICAL CORPORATION (US) | 1992-04-21 | — | — | US | disclosed |