Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 8/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.47 |
| ▸ | PTPN11 | Q06124 | 2/20 | 0.46 |
| ▸ | THRA | P10827 | 1/20 | 0.44 |
| ▸ | THRB | P10828 | 1/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.43 |
| ▸ | PKM | P14618 | 1/20 | 0.43 |
| ▸ | NR5A1 | Q13285 | 1/20 | 0.42 |
| ▸ | RARB | P10826 | 3/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.42 |
| ▸ | MEN1 | O00255 | 2/20 | 0.42 |
| ▸ | NR1I2 | O75469 | 1/20 | 0.42 |
| ▸ | LMNA | P02545 | 1/20 | 0.42 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.42 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.42 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.42 |
| ▸ | MAPT | P10636 | 1/20 | 0.42 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.42 |
| ▸ | HTR2B | P41595 | 1/20 | 0.42 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9729977 | 0.88 | THRA (0.45) | KDM4EALDH1A1PTPN11THRATHRB | |
| SCHEMBL9224451 | 0.82 | NR5A1 (0.56) | KDM4EALDH1A1PTPN11THRATHRB | |
| SCHEMBL9194398 | 0.82 | NR5A1 (0.56) | KDM4EALDH1A1PTPN11THRATHRB | |
| SCHEMBL9636694 | 0.82 | NR5A1 (0.56) | KDM4EALDH1A1PTPN11THRATHRB | |
| SCHEMBL28787801 | 0.81 | KDM4E (0.53) | KDM4EALDH1A1PTPN11SMN1; SMN2NR5A1 | |
| SCHEMBL6266863 | 0.78 | RARB (0.63) | KDM4EPTPN11THRATHRBRARB | |
| SCHEMBL3977527 | 0.78 | RARB (0.63) | KDM4EPTPN11THRATHRBRARB | |
| SCHEMBL9799861 | 0.78 | RARB (0.63) | KDM4EPTPN11THRATHRBRARB | |
| SCHEMBL8986580 | 0.78 | RARB (0.63) | KDM4EPTPN11THRATHRBRARB | |
| SCHEMBL10871804 | 0.78 | RARB (0.63) | KDM4EPTPN11THRATHRBRARB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5167863-A | Ferroelectricity; electrooptic switches | HITACHI, LTD. (JP) | 1992-12-01 | — | — | US | disclosed |