Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TACR1 | P25103 | 3/20 | 0.46 |
| ▸ | MEN1 | O00255 | 1/20 | 0.46 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.46 |
| ▸ | MAPT | P10636 | 1/20 | 0.46 |
| ▸ | TSHR | P16473 | 1/20 | 0.46 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.46 |
| ▸ | NAMPT | P43490 | 3/20 | 0.37 |
| ▸ | ASAH1 | Q13510 | 1/20 | 0.32 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.32 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.32 |
| ▸ | KEAP1 | Q14145 | 1/20 | 0.32 |
| ▸ | NFE2L2 | Q16236 | 1/20 | 0.32 |
| ▸ | MMP2 | P08253 | 1/20 | 0.32 |
| ▸ | MMP3 | P08254 | 1/20 | 0.32 |
| ▸ | MMP7 | P09237 | 1/20 | 0.32 |
| ▸ | MMP9 | P14780 | 1/20 | 0.32 |
| ▸ | MMP13 | P45452 | 1/20 | 0.32 |
| ▸ | MMP14 | P50281 | 1/20 | 0.32 |
| ▸ | TRPV1 | Q8NER1 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9729555 | 0.85 | TACR1 (0.50) | TACR1MEN1CYP3A4MAPTTSHR | |
| SCHEMBL9729350 | 0.84 | TACR1 (0.53) | TACR1MEN1CYP3A4MAPTTSHR | |
| SCHEMBL9730151 | 0.83 | TACR1 (0.52) | TACR1MEN1CYP3A4MAPTTSHR | |
| SCHEMBL9730495 | 0.82 | TACR1 (0.55) | TACR1MEN1CYP3A4MAPTTSHR | |
| SCHEMBL9730197 | 0.81 | TACR1 (0.53) | TACR1MEN1CYP3A4MAPTTSHR | |
| SCHEMBL9730371 | 0.81 | TACR1 (0.54) | TACR1MEN1CYP3A4MAPTTSHR | |
| SCHEMBL9729223 | 0.80 | TACR1 (0.56) | TACR1MEN1CYP3A4MAPTTSHR | |
| Iodide SCHEMBL9729835 | 0.79 | TACR1 (0.52) | TACR1MEN1CYP3A4MAPTTSHR | |
| SCHEMBL9730365 | 0.76 | TACR1 (0.51) | TACR1MEN1CYP3A4MAPTTSHR | |
| SCHEMBL9730899 | 0.76 | TACR1 (0.55) | TACR1MEN1CYP3A4MAPTTSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5102667-A | Antiallergens, antiinflammatory agents, nervous system disorders, immunology, psychological disorders | RHONE-POULENC SANTE (FR) | 1992-04-07 | — | — | US | disclosed |