SCHEMBL9730225

SCHEMBL9730225

CCCCO[C@@H](C)[C@@H](C)C(=O)O

nearest known ligand 0.46

Predicted protein targets (top 13)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 1/20 0.40
ATM Q13315 1/20 0.38
CA2 P00918 1/20 0.38
MAPK1 P28482 1/20 0.38
ACE2 Q9BYF1 1/20 0.37
HCAR2 Q8TDS4 1/20 0.37
PPARG P37231 2/20 0.37
PPARA Q07869 1/20 0.37
TP53 P04637 1/20 0.37
TSHR P16473 1/20 0.37
GPR84 Q9NQS5 3/20 0.36
FFAR1 O14842 1/20 0.36
PLA2G4B P0C869 1/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9730046 1.00 ALDH1A1 (0.40) ALDH1A1ATMCA2MAPK1ACE2
Hydrochloric Acid SCHEMBL9730267 0.98 ALDH1A1 (0.39) ALDH1A1ATMCA2MAPK1ACE2
Hydrochloric Acid SCHEMBL10513248 0.98 ALDH1A1 (0.39) ALDH1A1ATMCA2MAPK1ACE2
SCHEMBL9730119 0.92 ACE2 (0.43) ACE2HCAR2PPARGPPARATP53
SCHEMBL9730955 0.92 ACE2 (0.43) ACE2HCAR2PPARGPPARATP53
SCHEMBL9730313 0.92 ACE2 (0.43) ACE2HCAR2PPARGPPARATP53
SCHEMBL9730213 0.87 TDP1 (0.36) CA2MAPK1ACE2HCAR2TP53
SCHEMBL18265384 0.82 ALDH1A1 (0.48) ALDH1A1ATMMAPK1HCAR2TSHR
SCHEMBL9730264 0.82 ALDH1A1 (0.39) ALDH1A1ATMMAPK1TP53TSHR
SCHEMBL10513244 0.82 ALDH1A1 (0.39) ALDH1A1ATMMAPK1TP53TSHR

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-5167863-A Ferroelectricity; electrooptic switches HITACHI, LTD. (JP) 1992-12-01 US disclosed
EP-0341713-A2 Optically active compounds, liquid crystal compositions comprising said compounds, and liquid crystal optical modulators using said compositions HITACHI, LTD. (JP) 1989-11-15 EP disclosed
EP-0322862-A2 Optically active compounds, their preparation and their use in liquid crystal compositions and liquid crystal optical modulators HITACHI, LTD. (JP) 1989-07-05 EP disclosed