Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ACE2 | Q9BYF1 | 1/20 | 0.43 |
| ▸ | GPR84 | Q9NQS5 | 3/20 | 0.42 |
| ▸ | NAAA | Q02083 | 1/20 | 0.42 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.42 |
| ▸ | TP53 | P04637 | 1/20 | 0.42 |
| ▸ | TSHR | P16473 | 1/20 | 0.42 |
| ▸ | PPARG | P37231 | 2/20 | 0.41 |
| ▸ | PPARA | Q07869 | 1/20 | 0.41 |
| ▸ | CES2 | O00748 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 1/20 | 0.41 |
| ▸ | DNM1 | Q05193 | 1/20 | 0.41 |
| ▸ | LCK | P06239 | 1/20 | 0.41 |
| ▸ | PPARD | Q03181 | 1/20 | 0.41 |
| ▸ | ZDHHC20 | Q5W0Z9 | 1/20 | 0.41 |
| ▸ | ZDHHC2 | Q9UIJ5 | 1/20 | 0.41 |
| ▸ | PLA2G4B | P0C869 | 1/20 | 0.41 |
| ▸ | HCAR2 | Q8TDS4 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9730119 | 1.00 | ACE2 (0.43) | ACE2GPR84NAAAFFAR1TP53 | |
| SCHEMBL9730313 | 1.00 | ACE2 (0.43) | ACE2GPR84NAAAFFAR1TP53 | |
| SCHEMBL9730225 | 0.92 | ALDH1A1 (0.40) | ACE2GPR84FFAR1TP53TSHR | |
| SCHEMBL9730046 | 0.92 | ALDH1A1 (0.40) | ACE2GPR84FFAR1TP53TSHR | |
| Hydrochloric Acid SCHEMBL10513248 | 0.90 | ALDH1A1 (0.39) | ACE2GPR84FFAR1TP53TSHR | |
| Hydrochloric Acid SCHEMBL9730267 | 0.90 | ALDH1A1 (0.39) | ACE2GPR84FFAR1TP53TSHR | |
| SCHEMBL9730213 | 0.84 | TDP1 (0.36) | ACE2GPR84TP53HCAR2 | |
| SCHEMBL10590620 | 0.80 | HCAR2 (0.41) | ACE2GPR84NAAAFFAR1TP53 | |
| SCHEMBL9815330 | 0.80 | ACE2 (0.47) | ACE2GPR84FFAR1TP53TSHR | |
| SCHEMBL10593296 | 0.80 | HCAR2 (0.41) | ACE2GPR84NAAAFFAR1TP53 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5167863-A | Ferroelectricity; electrooptic switches | HITACHI, LTD. (JP) | 1992-12-01 | — | — | US | disclosed |
| EP-0322862-A2 | Optically active compounds, their preparation and their use in liquid crystal compositions and liquid crystal optical modulators | HITACHI, LTD. (JP) | 1989-07-05 | — | — | EP | disclosed |