Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.36 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.36 |
| ▸ | AKR1A1 | P14550 | 1/20 | 0.36 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.36 |
| ▸ | HTR2A | P28223 | 1/20 | 0.36 |
| ▸ | HTR2C | P28335 | 1/20 | 0.36 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.36 |
| ▸ | HRH1 | P35367 | 1/20 | 0.36 |
| ▸ | DRD3 | P35462 | 1/20 | 0.36 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.36 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.36 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.36 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.33 |
| ▸ | HCAR2 | Q8TDS4 | 1/20 | 0.33 |
| ▸ | TP53 | P04637 | 1/20 | 0.32 |
| ▸ | LMNA | P02545 | 1/20 | 0.31 |
| ▸ | ACE2 | Q9BYF1 | 1/20 | 0.31 |
| ▸ | CA2 | P00918 | 1/20 | 0.31 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.31 |
| ▸ | GPR84 | Q9NQS5 | 2/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9730046 | 0.87 | ALDH1A1 (0.40) | HCAR2TP53ACE2CA2MAPK1 | |
| SCHEMBL9730225 | 0.87 | ALDH1A1 (0.40) | HCAR2TP53ACE2CA2MAPK1 | |
| Hydrochloric Acid SCHEMBL10513248 | 0.85 | ALDH1A1 (0.39) | HCAR2TP53ACE2CA2MAPK1 | |
| Hydrochloric Acid SCHEMBL9730267 | 0.85 | ALDH1A1 (0.39) | HCAR2TP53ACE2CA2MAPK1 | |
| SCHEMBL9730955 | 0.84 | ACE2 (0.43) | HCAR2TP53ACE2GPR84 | |
| SCHEMBL9730313 | 0.84 | ACE2 (0.43) | HCAR2TP53ACE2GPR84 | |
| SCHEMBL9730119 | 0.84 | ACE2 (0.43) | HCAR2TP53ACE2GPR84 | |
| SCHEMBL9730369 | 0.81 | LMNA (0.39) | TDP1CHRM1AKR1A1CHRM3HTR2A | |
| SCHEMBL566390 | 0.81 | LMNA (0.39) | TDP1CHRM1AKR1A1CHRM3HTR2A | |
| SCHEMBL13015783 | 0.80 | HCAR2 (0.36) | TDP1CHRM1AKR1A1CHRM3HTR2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5167863-A | Ferroelectricity; electrooptic switches | HITACHI, LTD. (JP) | 1992-12-01 | — | — | US | disclosed |
| EP-0322862-A2 | Optically active compounds, their preparation and their use in liquid crystal compositions and liquid crystal optical modulators | HITACHI, LTD. (JP) | 1989-07-05 | — | — | EP | disclosed |