SCHEMBL9730274

SCHEMBL9730274

Nc1ccc(F)c(-n2nnn(CCCF)c2=O)c1

nearest known ligand 0.31

Predicted protein targets (top 2)

geneUniProtsupporting neighboursconfidence
BRD4 O60885 1/20 0.31
ROCK2 O75116 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL1943210 0.92 BRD4 (0.35) BRD4ROCK2
SCHEMBL10418842 0.90 ALDH1A1 (0.33)
SCHEMBL9731340 0.80 ALDH1A1 (0.38)
SCHEMBL9729973 0.80
SCHEMBL9873639 0.78 PDE7A (0.34)
SCHEMBL1943849 0.77 BRD4 (0.38) BRD4
SCHEMBL10521928 0.77 NLRP3 (0.33)
SCHEMBL9730340 0.77 BRPF1 (0.38) BRD4
SCHEMBL8582752 0.76 ESR1 (0.40)
SCHEMBL8411916 0.75 PTGES2 (0.34)

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-5136868-A HERBICIDAL 1-ARYL-4-SUBSTITUTED-1,4-DIHYDRO-5H-TETRAZOL-5-ONES AND SULFUR ANALOGS THEREOF FMC CORPORATION (US) 1992-08-11 US disclosed
US-4868321-A FOR HERBICIDES FMC CORPORATION (US) 1989-09-19 US disclosed
EP-0252982-A4 HERBICIDAL 1-ARYL-4-SUSTITUTTED-1,4-DIHYDRO-5H-TETRAZOL-5-ONES AND SULFUR ANALOGS THEREOF. FMC CORP (US) 1988-08-17 EP disclosed
EP-0252982-A1 HERBICIDAL 1-ARYL-4-SUSTITUTTED-1,4-DIHYDRO-5H-TETRAZOL-5-ONES AND SULFUR ANALOGS THEREOF FMC Corporation (US) 1988-01-20 EP disclosed
WO-1987003873-A1 HERBICIDAL 1-ARYL-4-SUBSTITUTED-1,4-DIHYDRO-5H-TETRAZOL-5-ONES AND SULFUR ANALOGS THEREOF FMC CORPORATION (US) 1987-07-02 WO disclosed