Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.47 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.47 |
| ▸ | TSHR | P16473 | 1/20 | 0.47 |
| ▸ | MME | P08473 | 2/20 | 0.42 |
| ▸ | ACE | P12821 | 1/20 | 0.42 |
| ▸ | CPA1 | P15085 | 1/20 | 0.42 |
| ▸ | ACE2 | Q9BYF1 | 1/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.41 |
| ▸ | MAPT | P10636 | 1/20 | 0.40 |
| ▸ | FAAH | O00519 | 3/20 | 0.39 |
| ▸ | GPR139 | Q6DWJ6 | 1/20 | 0.38 |
| ▸ | SLC6A5 | Q9Y345 | 1/20 | 0.37 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.35 |
| ▸ | RAB9A | P51151 | 1/20 | 0.34 |
| ▸ | HDAC3 | O15379 | 2/20 | 0.34 |
| ▸ | HDAC4 | P56524 | 2/20 | 0.34 |
| ▸ | HDAC1 | Q13547 | 2/20 | 0.34 |
| ▸ | HDAC7 | Q8WUI4 | 2/20 | 0.34 |
| ▸ | HDAC2 | Q92769 | 2/20 | 0.34 |
| ▸ | HDAC10 | Q969S8 | 2/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10447493 | 0.81 | ALDH1A1 (0.41) | ALDH1A1TSHRSMN1; SMN2MAPTFAAH | |
| SCHEMBL10555245 | 0.81 | GPR139 (0.33) | ALDH1A1KDM4ETSHRGPR139HDAC3 | |
| SCHEMBL6414278 | 0.76 | ALDH1A1 (0.47) | ALDH1A1KDM4ETSHRMMEACE | |
| SCHEMBL9638972 | 0.74 | GPR139 (0.34) | GPR139HDAC3HDAC4HDAC1HDAC7 | |
| SCHEMBL13301145 | 0.74 | FOLH1 (0.56) | — | |
| SCHEMBL9729998 | 0.74 | HDAC3 (0.37) | ALDH1A1KDM4EMMESMN1; SMN2MAPT | |
| SCHEMBL5315725 | 0.74 | ALDH1A1 (0.57) | ALDH1A1KDM4ETSHRMMEACE | |
| SCHEMBL8123489 | 0.74 | GPR139 (0.71) | ALDH1A1KDM4ETSHRMMESMN1; SMN2 | |
| SCHEMBL8123498 | 0.74 | GPR139 (0.71) | ALDH1A1KDM4ETSHRMMESMN1; SMN2 | |
| SCHEMBL6366655 | 0.74 | MME (0.47) | ALDH1A1KDM4ETSHRMMEACE |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5082930-A | Diagnosis, tumors | MALLINCKRODT MEDICAL, INC. (US) | 1992-01-21 | — | — | US | disclosed |