Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HDAC3 | O15379 | 1/20 | 0.37 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.37 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.37 |
| ▸ | HDAC7 | Q8WUI4 | 1/20 | 0.37 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.37 |
| ▸ | HDAC10 | Q969S8 | 1/20 | 0.37 |
| ▸ | HDAC11 | Q96DB2 | 1/20 | 0.37 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.37 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.37 |
| ▸ | HDAC9 | Q9UKV0 | 1/20 | 0.37 |
| ▸ | HDAC5 | Q9UQL6 | 1/20 | 0.37 |
| ▸ | MAPT | P10636 | 3/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.35 |
| ▸ | THRB | P10828 | 1/20 | 0.35 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.35 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.35 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.35 |
| ▸ | THPO | P40225 | 1/20 | 0.35 |
| ▸ | RECQL | P46063 | 1/20 | 0.35 |
| ▸ | BLM | P54132 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15099963 | 0.82 | MAPT (0.36) | MAPTKDM4ETHRBALOX15NFKB1 | |
| SCHEMBL13301142 | 0.80 | FOLH1 (0.52) | HDAC3HDAC4HDAC1HDAC7HDAC2 | |
| SCHEMBL13301145 | 0.79 | FOLH1 (0.56) | NOD1FOLH1NAALAD2RIMKLA | |
| SCHEMBL18197271 | 0.79 | HDAC3 (0.38) | HDAC3HDAC4HDAC1HDAC7HDAC2 | |
| SCHEMBL5239846 | 0.77 | NOD1 (0.56) | HDAC2NOD1MMECA2 | |
| SCHEMBL6381157 | 0.75 | GPR139 (0.58) | MAPTALDH1A1FOLH1GPR139 | |
| SCHEMBL2167433 | 0.74 | FOLH1 (0.55) | NOD1FOLH1CA2 | |
| SCHEMBL9730277 | 0.74 | ALDH1A1 (0.47) | HDAC3HDAC4HDAC1HDAC7HDAC2 | |
| SCHEMBL8084303 | 0.73 | NOD1 (0.49) | HDAC2NOD1FOLH1CA2 | |
| SCHEMBL9682745 | 0.73 | PAM (0.55) | MMENAALAD2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0247866-B1 | COUPLING AGENTS FOR RADIOLABELING PROTEINS | Mallinckrodt, Inc. (a Delaware corporation) (US) | 1990-11-14 | — | — | EP | claimed |
| US-5082930-A | Diagnosis, tumors | MALLINCKRODT MEDICAL, INC. (US) | 1992-01-21 | — | — | US | disclosed |
| EP-0247866-B1 | COUPLING AGENTS FOR RADIOLABELING PROTEINS | Mallinckrodt, Inc. (a Delaware corporation) (US) | 1990-11-14 | — | — | EP | disclosed |
| US-4861869-A | Coupling agents for joining radionuclide metal ions with biologically useful proteins | MALLINCKRODT, INC. (US) | 1989-08-29 | — | — | US | disclosed |
| EP-0247866-A1 | Coupling agents for radiolabeling proteins | Mallinckrodt, Inc. (a Delaware corporation) (US) | 1987-12-02 | — | — | EP | disclosed |