Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 4/20 | 0.61 |
| ▸ | MAPT | P10636 | 2/20 | 0.53 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.53 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.50 |
| ▸ | PRKCA | P17252 | 1/20 | 0.46 |
| ▸ | PRKCE | Q02156 | 1/20 | 0.46 |
| ▸ | PRKCQ | Q04759 | 1/20 | 0.46 |
| ▸ | PRKCD | Q05655 | 1/20 | 0.46 |
| ▸ | PAM | P19021 | 2/20 | 0.46 |
| ▸ | DGKA | P23743 | 1/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.45 |
| ▸ | DUSP3 | P51452 | 1/20 | 0.45 |
| ▸ | MEN1 | O00255 | 1/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9730544 | 0.98 | LMNA (0.65) | LMNAMAPTMAPK1ALDH1A1PRKCA | |
| SCHEMBL9730000 | 0.98 | LMNA (0.65) | LMNAMAPTMAPK1ALDH1A1PRKCA | |
| SCHEMBL9730181 | 0.94 | LMNA (0.53) | LMNAMAPTMAPK1ALDH1A1PRKCA | |
| SCHEMBL10053686 | 0.88 | LMNA (0.64) | LMNAMAPTMAPK1ALDH1A1PRKCA | |
| SCHEMBL10053675 | 0.86 | LMNA (0.68) | LMNAMAPTMAPK1ALDH1A1PRKCA | |
| SCHEMBL9730250 | 0.86 | ALDH1A1 (0.44) | LMNAMAPTMAPK1ALDH1A1PRKCA | |
| SCHEMBL17437789 | 0.82 | LMNA (0.62) | LMNAMAPTMAPK1ALDH1A1PRKCA | |
| SCHEMBL29174017 | 0.82 | LMNA (0.62) | LMNAMAPTMAPK1ALDH1A1PRKCA | |
| SCHEMBL28105010 | 0.82 | MAPT (0.59) | LMNAMAPTMAPK1ALDH1A1PRKCA | |
| SCHEMBL8618104 | 0.81 | LMNA (0.66) | LMNAMAPTMAPK1ALDH1A1PRKCA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5167863-A | Ferroelectricity; electrooptic switches | HITACHI, LTD. (JP) | 1992-12-01 | — | — | US | disclosed |
| EP-0322862-A2 | Optically active compounds, their preparation and their use in liquid crystal compositions and liquid crystal optical modulators | HITACHI, LTD. (JP) | 1989-07-05 | — | — | EP | disclosed |