Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 4/20 | 0.64 |
| ▸ | MAPT | P10636 | 3/20 | 0.60 |
| ▸ | MAPK1 | P28482 | 3/20 | 0.60 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.56 |
| ▸ | DGKA | P23743 | 1/20 | 0.52 |
| ▸ | PRKCA | P17252 | 1/20 | 0.51 |
| ▸ | PRKCE | Q02156 | 1/20 | 0.51 |
| ▸ | PRKCQ | Q04759 | 1/20 | 0.51 |
| ▸ | PRKCD | Q05655 | 1/20 | 0.51 |
| ▸ | CYP1A2 | P05177 | 3/20 | 0.49 |
| ▸ | TSHR | P16473 | 2/20 | 0.47 |
| ▸ | MEN1 | O00255 | 1/20 | 0.47 |
| ▸ | GMNN | O75496 | 1/20 | 0.47 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.47 |
| ▸ | BLM | P54132 | 1/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.47 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.47 |
| ▸ | NR1H4 | Q96RI1 | 1/20 | 0.47 |
| ▸ | TP53 | P04637 | 1/20 | 0.47 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10053675 | 0.98 | LMNA (0.68) | LMNAMAPTMAPK1ALDH1A1DGKA | |
| SCHEMBL10027719 | 0.91 | LMNA (0.59) | LMNAMAPTMAPK1ALDH1A1DGKA | |
| SCHEMBL14666487 | 0.91 | LMNA (0.59) | LMNAMAPTMAPK1ALDH1A1DGKA | |
| SCHEMBL9730330 | 0.88 | LMNA (0.61) | LMNAMAPTMAPK1ALDH1A1DGKA | |
| SCHEMBL16350413 | 0.88 | PRKCA (0.61) | LMNAMAPTALDH1A1DGKAPRKCA | |
| SCHEMBL9730544 | 0.87 | LMNA (0.65) | LMNAMAPTMAPK1ALDH1A1DGKA | |
| SCHEMBL9730000 | 0.87 | LMNA (0.65) | LMNAMAPTMAPK1ALDH1A1DGKA | |
| SCHEMBL29174017 | 0.85 | LMNA (0.62) | LMNAMAPTMAPK1ALDH1A1DGKA | |
| SCHEMBL17437789 | 0.85 | LMNA (0.62) | LMNAMAPTMAPK1ALDH1A1DGKA | |
| SCHEMBL28105010 | 0.85 | MAPT (0.59) | LMNAMAPTMAPK1ALDH1A1PRKCA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 14 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2121567-B1 | DIESTER-BASED LUBRICANTS AND METHODS OF MAKING SAME | CHEVRON USA INC (US) | 2016-08-10 | — | — | EP | disclosed |
| US-20160075872-A1 | Toughening of Anhydride Cured Thermosetting Epoxy Polymers Using Grafted Triglycerides | DREXEL UNIVERSITY (US) | 2016-03-17 | — | — | US | disclosed |
| US-8795547-B2 | Refrigeration oil from gas-to-liquid-derived and bio-derived triesters | CHEVRON U.S.A. INC. (US) | 2014-08-05 | — | — | US | disclosed |
| US-8585919-B2 | Refrigeration oil from gas-to-liquid derived and bio-derived diesters | CHEVRON U.S.A. INC. (US) | 2013-11-19 | — | — | US | disclosed |
| US-20130256586-A1 | REFRIGERATION OIL FROM GAS-TO-LIQUID-DERIVED AND BIO-DERIVED TRIESTERS | CHEVRON U.S.A., INC. | 2013-10-03 | — | — | US | disclosed |
| US-20130043424-A1 | REFRIGERATION OIL FROM GAS-TO-LIQUID DERIVED AND BIO-DERIVED DIESTERS | CHEVRON U.S.A. INC. (US) | 2013-02-21 | — | — | US | disclosed |
| US-8324423-B2 | Diester-based lubricants and methods of making same | CHEVRON U.S.A. INC. (US) | 2012-12-04 | — | — | US | disclosed |
| US-8268187-B2 | Refrigeration oil from gas-to-liquid-derived and bio-derived diesters | CHEVRON U.S.A. INC. (US) | 2012-09-18 | — | — | US | disclosed |
| US-20120018667-A1 | REFRIGERATION OIL FROM GAS-TO-LIQUID-DERIVED AND BIO-DERIVED DIESTERS | CHEVRON U.S.A., INC. | 2012-01-26 | — | — | US | disclosed |
| US-7871967-B2 | Diester-based lubricants and methods of making same | CHEVRON U.S.A. INC. (US) | 2011-01-18 | — | — | US | disclosed |
| US-20100261627-A1 | DIESTER-BASED LUBRICANTS AND METHODS OF MAKING SAME | CHEVRON U.S.A. INC. (US) | 2010-10-14 | — | — | US | disclosed |
| US-20090159837-A1 | REFRIGERATION OIL FROM GAS-TO-LIQUID-DERIVED AND BIO-DERIVED DIESTERS | CHEVRON U.S.A., INC. | 2009-06-25 | — | — | US | disclosed |
| US-20090159835-A1 | REFRIGERATION OIL FROM GAS-TO-LIQUID-DERIVED AND BIO-DERIVED TRIESTERS | CHEVRON U.S.A., INC. | 2009-06-25 | — | — | US | disclosed |
| US-20080194444-A1 | Diester-Based Lubricants and Methods of Making Same | CHEVRON U.S.A. INC. (US) | 2008-08-14 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20080194444-A1 | Diester-Based Lubricants and Methods of Making Same | DGAT2, DGAT1, FADS1 | LMNA 4799/4885MAPT 2489/4885MAPK1 3615/4885 |
| US-20100261627-A1 | DIESTER-BASED LUBRICANTS AND METHODS OF MAKING SAME | DGAT2, DGAT1, FADS1 | LMNA 4799/4885MAPT 2489/4885MAPK1 3615/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.