Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ABL1 | P00519 | 1/20 | 0.46 |
| ▸ | HTR2C | P28335 | 1/20 | 0.43 |
| ▸ | HTR2B | P41595 | 1/20 | 0.43 |
| ▸ | FFAR4 | Q5NUL3 | 6/20 | 0.42 |
| ▸ | FFAR1 | O14842 | 2/20 | 0.42 |
| ▸ | NPC1 | O15118 | 1/20 | 0.41 |
| ▸ | PKM | P14618 | 1/20 | 0.41 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.41 |
| ▸ | RAB9A | P51151 | 1/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.41 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.40 |
| ▸ | SCN3A | Q9NY46 | 1/20 | 0.40 |
| ▸ | MMP2 | P08253 | 1/20 | 0.40 |
| ▸ | MMP3 | P08254 | 1/20 | 0.40 |
| ▸ | MMP9 | P14780 | 1/20 | 0.40 |
| ▸ | MMP14 | P50281 | 1/20 | 0.40 |
| ▸ | SNCA | P37840 | 1/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.38 |
| ▸ | CACNA1B | Q00975 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Cyclopropane SCHEMBL9507570 | 0.83 | FFAR4 (0.46) | HTR2CHTR2BFFAR4FFAR1NPC1 | |
| SCHEMBL8959047 | 0.78 | PPARA (0.41) | NPC1PKMRAB9A | |
| SCHEMBL8959122 | 0.76 | ABL1 (0.43) | ABL1HTR2CHTR2BFFAR1NPC1 | |
| SCHEMBL8958993 | 0.76 | ABL1 (0.51) | ABL1HTR2CHTR2BFFAR4FFAR1 | |
| SCHEMBL10828131 | 0.75 | FFAR4 (0.56) | FFAR4FFAR1RAB9AKDM4E | |
| SCHEMBL10926665 | 0.74 | MAPT (0.48) | FFAR4FFAR1NPC1RAB9AMMP14 | |
| SCHEMBL9713896 | 0.73 | FFAR4 (0.59) | FFAR4FFAR1MMP2MMP3MMP9 | |
| SCHEMBL10879494 | 0.72 | FFAR1 (0.42) | HTR2CHTR2BFFAR4FFAR1MMP14 | |
| SCHEMBL9869869 | 0.72 | FFAR1 (0.53) | FFAR4FFAR1MMP2MMP3MMP9 | |
| SCHEMBL9486768 | 0.71 | MEN1 (0.62) | NPC1PKMEPHX2RAB9ASMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5132326-A | Insecticides which interfere with hormonal activity | BASF AKTIENGESELLSCHAFT (DE) | 1992-07-21 | — | — | US | claimed |
| JP-3135953-A | — | — | None | — | — | JP | disclosed |
| US-5132326-A | Insecticides which interfere with hormonal activity | BASF AKTIENGESELLSCHAFT (DE) | 1992-07-21 | — | — | US | disclosed |
| JP-H03135953-A | CYCLOPROPANETHIOCARBOXAMIDES | BASF AG | 1991-06-10 | — | — | JP | disclosed |