Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FFAR4 | Q5NUL3 | 3/20 | 0.46 |
| ▸ | FFAR1 | O14842 | 2/20 | 0.46 |
| ▸ | HTR2C | P28335 | 1/20 | 0.43 |
| ▸ | HTR2B | P41595 | 1/20 | 0.43 |
| ▸ | NPC1 | O15118 | 2/20 | 0.42 |
| ▸ | RAB9A | P51151 | 2/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.42 |
| ▸ | PKM | P14618 | 1/20 | 0.42 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.42 |
| ▸ | CACNA1B | Q00975 | 3/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.41 |
| ▸ | SIRT5 | Q9NXA8 | 1/20 | 0.40 |
| ▸ | MTNR1A | P48039 | 1/20 | 0.40 |
| ▸ | MTNR1B | P49286 | 1/20 | 0.40 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.39 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.39 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.39 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.39 |
| ▸ | HPGD | P15428 | 1/20 | 0.39 |
| ▸ | MMP2 | P08253 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9730441 | 0.83 | ABL1 (0.46) | FFAR4FFAR1HTR2CHTR2BNPC1 | |
| SCHEMBL11305595 | 0.82 | MTNR1A (0.56) | NPC1RAB9ASMN1; SMN2KDM4EMTNR1A | |
| SCHEMBL10828131 | 0.80 | FFAR4 (0.56) | FFAR4FFAR1RAB9AKDM4ESIRT5 | |
| SCHEMBL10828204 | 0.78 | L3MBTL1 (0.57) | MTNR1AMTNR1BHPGD | |
| SCHEMBL3363396 | 0.76 | MTNR1A (0.62) | NPC1RAB9ASMN1; SMN2PKMEPHX2 | |
| SCHEMBL10926665 | 0.76 | MAPT (0.48) | FFAR4FFAR1NPC1RAB9AKDM4E | |
| SCHEMBL10880149 | 0.76 | FFAR1 (0.44) | FFAR4FFAR1RAB9ASMN1; SMN2CACNA1B | |
| SCHEMBL9713896 | 0.75 | FFAR4 (0.59) | FFAR4FFAR1CACNA1BMMP2MMP3 | |
| SCHEMBL10879494 | 0.74 | FFAR1 (0.42) | FFAR4FFAR1HTR2CHTR2BCACNA1B | |
| SCHEMBL9869869 | 0.73 | FFAR1 (0.53) | FFAR4FFAR1CACNA1BMMP2MMP3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0412391-B1 | CYCLOPROPANE THIOCARBOXYLIC ACID AMIDES | BASF Aktiengesellschaft (DE) | 1993-09-29 | — | — | EP | disclosed |
| EP-0412391-A1 | Cyclopropane thiocarboxylic acid amides | BASF Aktiengesellschaft (DE) | 1991-02-13 | — | — | EP | disclosed |