SCHEMBL8959122

SCHEMBL8959122

S=C(NCCOc1ccc(Oc2cccc(Cl)c2)cc1Cl)C1CC1

nearest known ligand 0.43

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ABL1 P00519 1/20 0.43
KMT2A Q03164 2/20 0.40
MEN1 O00255 1/20 0.40
PKM P14618 1/20 0.40
PTGDR2 Q9Y5Y4 3/20 0.38
DRD2 P14416 2/20 0.38
DRD4 P21917 2/20 0.38
PPARD Q03181 2/20 0.38
PPARA Q07869 2/20 0.38
KLKB1 P03952 1/20 0.37
FFAR1 O14842 1/20 0.36
TP53 P04637 1/20 0.36
MAPK1 P28482 1/20 0.36
L3MBTL1 Q9Y468 1/20 0.36
DRD3 P35462 1/20 0.36
ALDH1A1 P00352 2/20 0.35
SLC6A4 P31645 1/20 0.35
HTR2C P28335 1/20 0.35
HTR2B P41595 1/20 0.35
NPC1 O15118 1/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8959068 0.88 ABL1 (0.53) ABL1KMT2AMEN1PKMPTGDR2
SCHEMBL8959047 0.84 PPARA (0.41) KMT2AMEN1PKMPTGDR2PPARD
SCHEMBL9163556 0.81 PPARD (0.47) KMT2AMEN1PKMDRD2DRD4
SCHEMBL9157470 0.80 PDE4A (0.41) ABL1KMT2AMEN1PKMPTGDR2
SCHEMBL9160000 0.80 MAPT (0.46) KMT2AMEN1PKMPPARDPPARA
SCHEMBL8959189 0.79 PKM (0.56) ABL1KMT2AMEN1PKMPTGDR2
SCHEMBL8959167 0.78 KMT2A (0.50) ABL1KMT2AMEN1PKMPPARD
SCHEMBL8958993 0.78 ABL1 (0.51) ABL1KMT2AMEN1PKMPPARD
SCHEMBL8959019 0.77 HPGD (0.39) ABL1KMT2AMEN1PKMPTGDR2
SCHEMBL9163309 0.77 PPARD (0.43) KMT2AMEN1PKMPPARDPPARA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0514833-B1 Amide derivatives, their production processes and their compositions for the control of insect pests SUMITOMO CHEMICAL CO (JP) 1996-01-17 EP disclosed
US-5364966-A Amide derivatives, their production processes and their compositions for the control of insect pests SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 1994-11-15 US disclosed
US-5356930-A Amide derivatives, their production processes and their compositions for the control of insect pests SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 1994-10-18 US disclosed
EP-0514833-A2 Amide derivatives, their production processes and their compositions for the control of insect pests SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 1992-11-25 EP disclosed