Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 2/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.40 |
| ▸ | FAAH | O00519 | 1/20 | 0.37 |
| ▸ | TP53 | P04637 | 1/20 | 0.37 |
| ▸ | TSHR | P16473 | 1/20 | 0.37 |
| ▸ | NOX1 | Q9Y5S8 | 1/20 | 0.36 |
| ▸ | RXRA | P19793 | 1/20 | 0.36 |
| ▸ | PLA2G4B | P0C869 | 1/20 | 0.36 |
| ▸ | HCAR3 | P49019 | 1/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.36 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9730460 | 1.00 | MAPT (0.40) | MAPTALDH1A1FAAHTP53TSHR | |
| SCHEMBL9141569 | 0.88 | MAPT (0.55) | MAPTALDH1A1TP53TSHRRXRA | |
| SCHEMBL9730406 | 0.88 | MAPT (0.55) | MAPTALDH1A1TP53TSHRRXRA | |
| SCHEMBL7555804 | 0.81 | MAPT (0.50) | MAPTALDH1A1TP53TSHRPLA2G4B | |
| SCHEMBL9730675 | 0.80 | MAPT (0.57) | MAPTALDH1A1TP53TSHRPLA2G4B | |
| SCHEMBL9730402 | 0.80 | MAPT (0.57) | MAPTALDH1A1TP53TSHRPLA2G4B | |
| SCHEMBL10356272 | 0.80 | GPR88 (0.46) | MAPTALDH1A1FAAHTP53TSHR | |
| SCHEMBL5096563 | 0.80 | GPR88 (0.46) | MAPTALDH1A1FAAHTP53TSHR | |
| SCHEMBL7080085 | 0.77 | RAB9A (0.41) | MAPTALDH1A1FAAHKDM4EL3MBTL1 | |
| SCHEMBL10455055 | 0.76 | RARB (0.48) | MAPTALDH1A1FAAHTP53TSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5145601-A | Ferroelectric liquid crystals with nicotinic acid cores | THE UNIVERSITY OF COLORADO FOUNDATION INC. (US) | 1992-09-08 | — | — | US | disclosed |