Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GBA1 | P04062 | 3/20 | 0.62 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.59 |
| ▸ | HPGD | P15428 | 1/20 | 0.55 |
| ▸ | MEN1 | O00255 | 1/20 | 0.54 |
| ▸ | P2RY12 | Q9H244 | 1/20 | 0.54 |
| ▸ | HTT | P42858 | 2/20 | 0.53 |
| ▸ | POLB | P06746 | 1/20 | 0.53 |
| ▸ | CKS1B | P61024 | 1/20 | 0.53 |
| ▸ | SKP1 | P63208 | 1/20 | 0.53 |
| ▸ | SKP2 | Q13309 | 1/20 | 0.53 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.53 |
| ▸ | LMNA | P02545 | 1/20 | 0.53 |
| ▸ | MAPT | P10636 | 1/20 | 0.53 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.53 |
| ▸ | SLC6A7 | Q99884 | 2/20 | 0.52 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.52 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.52 |
| ▸ | DPP4 | P27487 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9731153 | 0.86 | ALDH1A1 (0.57) | KDM4EHPGDMEN1HTTPOLB | |
| SCHEMBL18362065 | 0.81 | LOXL2 (0.67) | GBA1KDM4EMEN1P2RY12CKS1B | |
| SCHEMBL18362066 | 0.81 | MEN1 (0.50) | GBA1KDM4EMEN1CKS1BSKP1 | |
| SCHEMBL12051485 | 0.80 | GBA1 (0.57) | GBA1KDM4ECKS1BSKP1SKP2 | |
| Hydrochloric Acid SCHEMBL20337903 | 0.80 | LOXL2 (0.65) | GBA1KDM4EMEN1P2RY12CKS1B | |
| SCHEMBL13115595 | 0.77 | KDM4E (0.67) | GBA1KDM4EHPGDMEN1HTT | |
| SCHEMBL9513674 | 0.76 | KDM4E (0.59) | GBA1KDM4EHPGDCKS1BSKP1 | |
| SCHEMBL12082726 | 0.74 | KDM4E (1.00) | KDM4EHPGDMEN1HTTPOLB | |
| SCHEMBL252026 | 0.73 | HPGD (0.79) | KDM4EHPGDMEN1POLBALDH1A1 | |
| SCHEMBL7129676 | 0.73 | HPGD (0.79) | KDM4EHPGDMEN1POLBALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5138058-A | Diabetic screening | HOECHST AKTIENGESELLSCHAFT (DE) | 1992-08-11 | — | — | US | disclosed |
| EP-0384370-A1 | Substituted pyrimidine derivatives, process for their preparation, and their use as tool | HOECHST AKTIENGESELLSCHAFT (DE) | 1990-08-29 | — | — | EP | disclosed |