SCHEMBL9730563

SCHEMBL9730563

CCC(=O)OC(C)C(C)O

nearest known ligand 0.37

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MEN1 O00255 1/20 0.37
CYP2C19 P33261 1/20 0.37
RECQL P46063 1/20 0.37
KMT2A Q03164 1/20 0.37
ALDH1A1 P00352 2/20 0.35
LMNA P02545 2/20 0.34
ESR1 P03372 1/20 0.34
HIF1A Q16665 1/20 0.34
NAAA Q02083 1/20 0.32
ALOX15 P16050 1/20 0.32
MAPT P10636 1/20 0.31
TSHR P16473 2/20 0.31
TDP1 Q9NUW8 2/20 0.30
FFAR3 O14843 1/20 0.30
MMP1 P03956 1/20 0.30
MMP2 P08253 1/20 0.30
MMP3 P08254 1/20 0.30
MMP9 P14780 1/20 0.30
MMP13 P45452 1/20 0.30
ABCB1 P08183 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL12205685 1.00 MEN1 (0.37) MEN1CYP2C19RECQLKMT2AALDH1A1
SCHEMBL23249534 1.00 MEN1 (0.37) MEN1CYP2C19RECQLKMT2AALDH1A1
SCHEMBL15186967 0.87 MEN1 (0.41) MEN1CYP2C19RECQLKMT2AALDH1A1
SCHEMBL24805426 0.87 MEN1 (0.41) MEN1CYP2C19RECQLKMT2AALDH1A1
SCHEMBL11016719 0.82 LMNA (0.40) MEN1KMT2AALDH1A1LMNAMAPT
SCHEMBL685676 0.82 MEN1 (0.38) MEN1CYP2C19RECQLKMT2AALDH1A1
SCHEMBL9730948 0.81 ALDH1A1 (0.48) ALDH1A1LMNAALOX15MAPTTSHR
SCHEMBL5707872 0.80 MEN1 (0.37) MEN1CYP2C19RECQLKMT2AALDH1A1
SCHEMBL821959 0.80 TDP1 (0.36) LMNAMAPTTSHRTDP1MMP1
SCHEMBL3608777 0.79

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 14 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-12281076-B2 Process for synthesis of picolinamides CORTEVA AGRISCIENCE LLC (US) 2025-04-22 US disclosed
US-20220411375-A1 PROCESS FOR SYNTHESIS OF PICOLINAMIDES CORTEVA AGRISCIENCE LLC (US) 2022-12-29 US disclosed
EP-4044811-A1 PROCESS FOR SYNTHESIS OF PICOLINAMIDES Corteva Agriscience LLC (US) 2022-08-24 EP disclosed
CN-114554848-A Process for the synthesis of picolinamides 科迪华农业科技有限责任公司 2022-05-27 CN disclosed
EP-3958678-A1 PEST CONTROL INCLUDING COMBINED MATING DISRUPTION AND TRAPPING Trece, Inc. (US) 2022-03-02 EP disclosed
US-20220039380-A1 PEST CONTROL INCLUDING COMBINED MATING DISRUPTION AND TRAPPING TRECE 2022-02-10 US disclosed
WO-2021076681-A1 PROCESS FOR SYNTHESIS OF PICOLINAMIDES DOW AGROSCIENCES LLC (US) 2021-04-22 WO disclosed
WO-2020220022-A1 PEST CONTROL INCLUDING COMBINED MATING DISRUPTION AND TRAPPING TRECE, INC. (US) 2020-10-29 WO disclosed
CN-103193636-B A kind of method of synthesizing 2,3-butanediol ester HUNAN CHANGLING PETROCHEMICAL TECHNOLOGY DEVELOPMENT CO., LTD. (CN) 2016-01-13 CN disclosed
US-9018409-B2 Process for functionalization of unsaturated compounds MEURICE R&D ASBL (BE) 2015-04-28 US disclosed
US-20130211033-A1 PROCESS FOR FUNCTIONALIZATION OF UNSATURATED COMPOUNDS MEURICE R&D ASBL (BE) 2013-08-15 US disclosed
US-20110039066-A1 SELF-CLEANING SURFACES AIRBUS UK LIMITED (GB) 2011-02-17 US disclosed
US-5167863-A Ferroelectricity; electrooptic switches HITACHI, LTD. (JP) 1992-12-01 US disclosed
EP-0322862-A2 Optically active compounds, their preparation and their use in liquid crystal compositions and liquid crystal optical modulators HITACHI, LTD. (JP) 1989-07-05 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20110039066-A1 SELF-CLEANING SURFACES ICOSLG, PDCD1LG2, EPCAM MEN1 3317/4885CYP2C19 4555/4885RECQL 3507/4885
US-20220411375-A1 PROCESS FOR SYNTHESIS OF PICOLINAMIDES NPEPPS, ANPEP, DNPEP MEN1 921/4885CYP2C19 390/4885RECQL 4552/4885
US-20130211033-A1 PROCESS FOR FUNCTIONALIZATION OF UNSATURATED COMPOUNDS F10, RPP30, PUF60 MEN1 4084/4885CYP2C19 371/4885RECQL 1170/4885
US-12281076-B2 Process for synthesis of picolinamides NPEPPS, ANPEP, DNPEP MEN1 921/4885CYP2C19 390/4885RECQL 4552/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.