Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 6/20 | 0.67 |
| ▸ | KMT2A | Q03164 | 6/20 | 0.67 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.60 |
| ▸ | HPGD | P15428 | 3/20 | 0.59 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.59 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.59 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.59 |
| ▸ | NPC1 | O15118 | 1/20 | 0.59 |
| ▸ | RAB9A | P51151 | 1/20 | 0.59 |
| ▸ | ATM | Q13315 | 1/20 | 0.59 |
| ▸ | MAPT | P10636 | 2/20 | 0.56 |
| ▸ | GAA | P10253 | 1/20 | 0.56 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.55 |
| ▸ | OR51E2 | Q9H255 | 1/20 | 0.55 |
| ▸ | TTR | P02766 | 1/20 | 0.53 |
| ▸ | LMNA | P02545 | 1/20 | 0.51 |
| ▸ | HTT | P42858 | 1/20 | 0.51 |
| ▸ | TP53 | P04637 | 1/20 | 0.51 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.51 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.51 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1840837 | 0.92 | MEN1 (0.67) | MEN1KMT2ACYP19A1HPGDSMN1; SMN2 | |
| SCHEMBL2292369 | 0.92 | CYP19A1 (0.71) | MEN1KMT2ACYP19A1HPGDSMN1; SMN2 | |
| SCHEMBL30129997 | 0.92 | CYP19A1 (0.71) | MEN1KMT2ACYP19A1HPGDSMN1; SMN2 | |
| SCHEMBL31511909 | 0.92 | MEN1 (0.67) | MEN1KMT2ACYP19A1HPGDSMN1; SMN2 | |
| SCHEMBL1039742 | 0.86 | SMN1; SMN2 (0.70) | MEN1KMT2AHPGDSMN1; SMN2ALDH1A1 | |
| SCHEMBL29828287 | 0.85 | KMT2A (0.61) | MEN1KMT2ACYP19A1SMN1; SMN2ALDH1A1 | |
| SCHEMBL10829624 | 0.85 | KMT2A (0.61) | MEN1KMT2ACYP19A1SMN1; SMN2ALDH1A1 | |
| SCHEMBL4656453 | 0.85 | MEN1 (0.76) | MEN1KMT2ACYP19A1HPGDSMN1; SMN2 | |
| SCHEMBL31511903 | 0.85 | MEN1 (0.76) | MEN1KMT2ACYP19A1HPGDSMN1; SMN2 | |
| SCHEMBL21643384 | 0.84 | MEN1 (0.60) | MEN1KMT2ACYP19A1HPGDSMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5151420-A | Cardiovascular disorders | ORION CORPORATION/ORION PHARMACEUTICA (FI) | 1992-09-29 | — | — | US | disclosed |