Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 3/20 | 0.76 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.76 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.76 |
| ▸ | NPC1 | O15118 | 1/20 | 0.76 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.76 |
| ▸ | HPGD | P15428 | 1/20 | 0.76 |
| ▸ | RAB9A | P51151 | 1/20 | 0.76 |
| ▸ | ATM | Q13315 | 1/20 | 0.76 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.76 |
| ▸ | SLC5A1 | P13866 | 2/20 | 0.69 |
| ▸ | SLC5A2 | P31639 | 2/20 | 0.69 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.67 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.67 |
| ▸ | RELA | Q04206 | 1/20 | 0.67 |
| ▸ | F2RL1 | P55085 | 1/20 | 0.58 |
| ▸ | GAA | P10253 | 1/20 | 0.55 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.55 |
| ▸ | MAPT | P10636 | 1/20 | 0.55 |
| ▸ | PPARG | P37231 | 1/20 | 0.55 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.55 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31511903 | 1.00 | MEN1 (0.76) | MEN1KMT2ACYP3A4NPC1ALDH1A1 | |
| SCHEMBL30254972 | 0.93 | KMT2A (0.69) | MEN1KMT2ACYP3A4NPC1ALDH1A1 | |
| SCHEMBL2875989 | 0.93 | KMT2A (0.69) | MEN1KMT2ACYP3A4NPC1ALDH1A1 | |
| Davidigenin SCHEMBL750182 | 0.88 | CYP19A1 (0.70) | MEN1KMT2ACYP3A4NPC1ALDH1A1 | |
| Davidigenin SCHEMBL30291870 | 0.88 | CYP19A1 (0.70) | MEN1KMT2ACYP3A4NPC1ALDH1A1 | |
| Ononetin SCHEMBL30203900 | 0.87 | NPC1 (1.00) | MEN1KMT2ACYP3A4NPC1ALDH1A1 | |
| Ononetin SCHEMBL2948430 | 0.87 | NPC1 (1.00) | MEN1KMT2ACYP3A4NPC1ALDH1A1 | |
| SCHEMBL10829584 | 0.85 | TSHR (0.63) | MEN1KMT2ACYP3A4NPC1ALDH1A1 | |
| SCHEMBL9730692 | 0.85 | MEN1 (0.67) | MEN1KMT2ACYP3A4NPC1ALDH1A1 | |
| SCHEMBL1840837 | 0.85 | MEN1 (0.67) | MEN1KMT2ACYP3A4NPC1ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 27 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20230045522-A1 | COMPOSITIONS AND METHODS TO MODULATE GLUCOSE HOMEOSTASIS | NATIONAL INSTITUTES OF HEALTH (NIH), U.S. DEPT. OF HEALTH AND HUMAN SERVICES (DHHS), U.S. GOVERNMENT | 2023-02-09 | — | — | US | claimed |
| WO-2021113473-A1 | COMPOSITIONS AND METHODS TO MODULATE GLUCOSE HOMEOSTASIS | THE BOARD OF SUPERVISORS OF LOUISIANA STATE UNIVERSITY AND AGRICULTURAL AND MECHANICAL COLLEGE (US) | 2021-06-10 | — | — | WO | claimed |
| EP-1996212-A2 | COMPOUNDS FROM AN EXTRACT OF ARTEMISIA AND METHODS FOR TREATING DISORDERS | Rutgers, The State University of New Jersey (US) | 2008-12-03 | — | — | EP | claimed |
| WO-2007109217-A2 | COMPOUNDS FROM AN EXTRACT OF ARTEMISIA AND METHODS FOR TREATING DISORDERS | RUTGERS, THE STATES UNIVERSITY OF NEW JERSEY (US) | 2007-09-27 | — | — | WO | claimed |
| US-20070224301-A1 | Compounds from an extract of Artemisia and methods for treating disorders | RUTGERS, THE STATE UNIVERSITY OF NEW JERSEY | 2007-09-27 | — | — | US | claimed |
| US-20230293614-A1 | COMPOSITIONS AND METHODS OF TREATING UPS-ASSOCIATED DISEASES | NATIONAL INSTITUTES OF HEALTH (NIH), U.S. DEPT. OF HEALTH AND HUMAN SERVICES (DHHS), U.S. GOVERNMENT | 2023-09-21 | — | — | US | disclosed |
| US-20230045522-A1 | COMPOSITIONS AND METHODS TO MODULATE GLUCOSE HOMEOSTASIS | NATIONAL INSTITUTES OF HEALTH (NIH), U.S. DEPT. OF HEALTH AND HUMAN SERVICES (DHHS), U.S. GOVERNMENT | 2023-02-09 | — | — | US | disclosed |
| US-20230045522-A1 | COMPOSITIONS AND METHODS TO MODULATE GLUCOSE HOMEOSTASIS | NATIONAL INSTITUTES OF HEALTH (NIH), U.S. DEPT. OF HEALTH AND HUMAN SERVICES (DHHS), U.S. GOVERNMENT | 2023-02-09 | — | — | US | disclosed |
| WO-2023278394-A1 | POLYCATIONIC SALTS OF PHENOLIC COMPOUNDS AND USES THEREOF | FIRMENICH INCORPORATED (US) | 2023-01-05 | — | — | WO | disclosed |
| WO-2021113473-A1 | COMPOSITIONS AND METHODS TO MODULATE GLUCOSE HOMEOSTASIS | THE BOARD OF SUPERVISORS OF LOUISIANA STATE UNIVERSITY AND AGRICULTURAL AND MECHANICAL COLLEGE (US) | 2021-06-10 | — | — | WO | disclosed |
| US-8992892-B2 | Use of 1-(2,4-dihydroxy-phenyl)-3-(3-hydroxy-4-methoxy-phenyl)-propan-1-one | SYMRISE AG (DE) | 2015-03-31 | — | — | US | disclosed |
| US-8992892-B2 | Use of 1-(2,4-dihydroxy-phenyl)-3-(3-hydroxy-4-methoxy-phenyl)-propan-1-one | SYMRISE AG (DE) | 2015-03-31 | — | — | US | disclosed |
| WO-2007109217-A3 | COMPOUNDS FROM AN EXTRACT OF ARTEMISIA AND METHODS FOR TREATING DISORDERS | RUTGERS THE STATES UNIVERSITY (US) | 2008-01-17 | — | — | WO | disclosed |
| WO-2007109217-A2 | COMPOUNDS FROM AN EXTRACT OF ARTEMISIA AND METHODS FOR TREATING DISORDERS | RUTGERS, THE STATES UNIVERSITY OF NEW JERSEY (US) | 2007-09-27 | — | — | WO | disclosed |
| WO-2007109217-A2 | COMPOUNDS FROM AN EXTRACT OF ARTEMISIA AND METHODS FOR TREATING DISORDERS | RUTGERS, THE STATES UNIVERSITY OF NEW JERSEY (US) | 2007-09-27 | — | — | WO | disclosed |
| WO-2007109217-A2 | COMPOUNDS FROM AN EXTRACT OF ARTEMISIA AND METHODS FOR TREATING DISORDERS | RUTGERS, THE STATES UNIVERSITY OF NEW JERSEY (US) | 2007-09-27 | — | — | WO | disclosed |
| US-20070224301-A1 | Compounds from an extract of Artemisia and methods for treating disorders | RUTGERS, THE STATE UNIVERSITY OF NEW JERSEY | 2007-09-27 | — | — | US | disclosed |
| US-20070224301-A1 | Compounds from an extract of Artemisia and methods for treating disorders | RUTGERS, THE STATE UNIVERSITY OF NEW JERSEY | 2007-09-27 | — | — | US | disclosed |
| US-20070224301-A1 | Compounds from an extract of Artemisia and methods for treating disorders | RUTGERS, THE STATE UNIVERSITY OF NEW JERSEY | 2007-09-27 | — | — | US | disclosed |
| US-20070224301-A1 | Compounds from an extract of Artemisia and methods for treating disorders | RUTGERS, THE STATE UNIVERSITY OF NEW JERSEY | 2007-09-27 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20070224301-A1 | Compounds from an extract of Artemisia and methods for treating disorders | PDK2, PCK2, DUSP2 | MEN1 3925/4885KMT2A 1873/4885CYP3A4 2330/4885 |
| US-20230045522-A1 | COMPOSITIONS AND METHODS TO MODULATE GLUCOSE HOMEOSTASIS | GCKR, G6PC1, GPR119 | MEN1 1345/4885KMT2A 3878/4885CYP3A4 4265/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.