Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALOX5 | P09917 | 5/20 | 0.64 |
| ▸ | CA12 | O43570 | 1/20 | 0.40 |
| ▸ | CA1 | P00915 | 1/20 | 0.40 |
| ▸ | CA2 | P00918 | 1/20 | 0.40 |
| ▸ | CA9 | Q16790 | 1/20 | 0.40 |
| ▸ | SPHK2 | Q9NRA0 | 1/20 | 0.38 |
| ▸ | SPHK1 | Q9NYA1 | 1/20 | 0.38 |
| ▸ | MAOB | P27338 | 5/20 | 0.38 |
| ▸ | MAOA | P21397 | 3/20 | 0.38 |
| ▸ | BCHE | P06276 | 2/20 | 0.37 |
| ▸ | GSK3B | P49841 | 1/20 | 0.37 |
| ▸ | BACE1 | P56817 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9731145 | 0.94 | ALOX5 (0.65) | ALOX5CA12CA1CA2CA9 | |
| Formamide SCHEMBL9729963 | 0.87 | ALOX5 (0.62) | ALOX5 | |
| SCHEMBL9729627 | 0.79 | ALOX5 (0.59) | ALOX5CA12CA1CA2CA9 | |
| Formamide SCHEMBL9729701 | 0.78 | ALOX5 (0.62) | ALOX5CA12CA1CA2CA9 | |
| SCHEMBL9730761 | 0.78 | ALOX5 (1.00) | ALOX5 | |
| SCHEMBL9729866 | 0.71 | ALOX5 (0.63) | ALOX5CA12CA1CA2CA9 | |
| Formamide SCHEMBL9729640 | 0.69 | ALDH1A1 (0.53) | ALOX5 | |
| Formamide SCHEMBL9730285 | 0.69 | ALOX5 (0.67) | ALOX5MAOBMAOA | |
| Formamide SCHEMBL9729662 | 0.68 | ALOX5 (0.64) | ALOX5MAOBMAOA | |
| SCHEMBL15052427 | 0.65 | PARP1 (0.61) | ALOX5MAOBMAOA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5155130-A | Lipoxygenase inhibitors | CIBA-GEIGY CORPORATION (US) | 1992-10-13 | — | — | US | disclosed |