Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.53 |
| ▸ | ALOX5 | P09917 | 6/20 | 0.51 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.45 |
| ▸ | MTNR1A | P48039 | 2/20 | 0.45 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.42 |
| ▸ | GPR132 | Q9UNW8 | 1/20 | 0.40 |
| ▸ | PRMT5 | O14744 | 1/20 | 0.40 |
| ▸ | WDR77 | Q9BQA1 | 1/20 | 0.40 |
| ▸ | BRD4 | O60885 | 1/20 | 0.39 |
| ▸ | CREBBP | Q92793 | 1/20 | 0.39 |
| ▸ | LMNA | P02545 | 1/20 | 0.38 |
| ▸ | RECQL | P46063 | 1/20 | 0.38 |
| ▸ | MMP13 | P45452 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Formamide SCHEMBL9729701 | 0.89 | ALOX5 (0.62) | ALOX5MTNR1A | |
| SCHEMBL9729866 | 0.83 | ALOX5 (0.63) | ALOX5MTNR1A | |
| Formamide SCHEMBL9730285 | 0.81 | ALOX5 (0.67) | ALOX5KMT2AMTNR1A | |
| Formamide SCHEMBL9729662 | 0.81 | ALOX5 (0.64) | ALOX5MTNR1A | |
| SCHEMBL9729637 | 0.80 | ALOX5 (0.80) | ALDH1A1ALOX5 | |
| SCHEMBL6165724 | 0.78 | ALDH1A1 (0.45) | ALDH1A1ALOX5KMT2AMTNR1A | |
| Formamide SCHEMBL9729455 | 0.78 | ALOX5 (0.60) | ALOX5MTNR1A | |
| Urea SCHEMBL9730233 | 0.76 | MTNR1A (0.68) | ALOX5KMT2AMTNR1AMAPK1 | |
| Formamide SCHEMBL9729689 | 0.76 | ALOX5 (0.63) | ALOX5MTNR1A | |
| SCHEMBL9729952 | 0.75 | ALOX5 (0.67) | ALOX5KMT2AMTNR1A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5155130-A | Lipoxygenase inhibitors | CIBA-GEIGY CORPORATION (US) | 1992-10-13 | — | — | US | disclosed |