Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RORC | P51449 | 6/20 | 0.41 |
| ▸ | IDO1 | P14902 | 3/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.39 |
| ▸ | CDK9 | P50750 | 1/20 | 0.38 |
| ▸ | P2RX7 | Q99572 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.35 |
| ▸ | NAMPT | P43490 | 2/20 | 0.35 |
| ▸ | THRB | P10828 | 1/20 | 0.35 |
| ▸ | ATM | Q13315 | 1/20 | 0.35 |
| ▸ | POLB | P06746 | 1/20 | 0.34 |
| ▸ | JAK2 | O60674 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9729842 | 0.90 | RORC (0.40) | RORCIDO1KMT2ACDK9P2RX7 | |
| SCHEMBL9729525 | 0.90 | RAB9A (0.42) | RORCIDO1KMT2AALDH1A1POLB | |
| SCHEMBL9730198 | 0.88 | IDO1 (0.37) | RORCIDO1KMT2ACDK9P2RX7 | |
| SCHEMBL9729554 | 0.87 | IDO1 (0.42) | RORCIDO1KMT2ACDK9P2RX7 | |
| SCHEMBL9729153 | 0.82 | IDO1 (0.39) | RORCIDO1KMT2ACDK9P2RX7 | |
| SCHEMBL10907970 | 0.80 | RAB9A (0.44) | RORCIDO1KMT2AALDH1A1POLB | |
| SCHEMBL9730088 | 0.80 | RAB9A (0.41) | RORCIDO1KMT2AALDH1A1POLB | |
| SCHEMBL9729766 | 0.78 | RAB9A (0.41) | IDO1KMT2AALDH1A1POLB | |
| SCHEMBL9730099 | 0.77 | IDO1 (0.35) | RORCIDO1KMT2ACDK9P2RX7 | |
| SCHEMBL3066779 | 0.77 | RAB9A (0.47) | IDO1KMT2AALDH1A1POLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0445069-A1 | Heterocyclic compounds | CIBA-GEIGY AG (CH) | 1991-09-04 | — | — | EP | claimed |
| US-5171354-A | Herbicides | CIBA-GEIGY CORPORATION (US) | 1992-12-15 | — | — | US | disclosed |
| EP-0445069-A1 | Heterocyclic compounds | CIBA-GEIGY AG (CH) | 1991-09-04 | — | — | EP | disclosed |