Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | IDO1 | P14902 | 3/20 | 0.39 |
| ▸ | NAMPT | P43490 | 3/20 | 0.36 |
| ▸ | CDK9 | P50750 | 1/20 | 0.36 |
| ▸ | P2RX7 | Q99572 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.35 |
| ▸ | RORC | P51449 | 1/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.35 |
| ▸ | ATM | Q13315 | 1/20 | 0.35 |
| ▸ | POLB | P06746 | 1/20 | 0.34 |
| ▸ | MEN1 | O00255 | 1/20 | 0.34 |
| ▸ | HTT | P42858 | 2/20 | 0.33 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.33 |
| ▸ | MAPT | P10636 | 1/20 | 0.33 |
| ▸ | GAA | P10253 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9729497 | 0.90 | RAB9A (0.42) | IDO1ALDH1A1KMT2APOLBMEN1 | |
| SCHEMBL9729554 | 0.87 | IDO1 (0.42) | IDO1NAMPTCDK9P2RX7ALDH1A1 | |
| SCHEMBL9730033 | 0.86 | CYP11B2 (0.41) | IDO1NAMPTALDH1A1RORCHTT | |
| SCHEMBL9730099 | 0.85 | IDO1 (0.35) | IDO1NAMPTCDK9P2RX7ALDH1A1 | |
| SCHEMBL9730768 | 0.82 | RORC (0.41) | IDO1NAMPTCDK9P2RX7ALDH1A1 | |
| SCHEMBL9730198 | 0.80 | IDO1 (0.37) | IDO1NAMPTCDK9P2RX7ALDH1A1 | |
| SCHEMBL9723814 | 0.80 | RAB9A (0.44) | IDO1P2RX7ALDH1A1KMT2APOLB | |
| SCHEMBL9729510 | 0.78 | NAPRT (0.37) | IDO1P2RX7ALDH1A1CYP19A1 | |
| SCHEMBL9853671 | 0.78 | CYP19A1 (0.40) | ALDH1A1POLBCYP19A1 | |
| SCHEMBL9729842 | 0.78 | RORC (0.40) | IDO1NAMPTCDK9P2RX7ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0445069-A1 | Heterocyclic compounds | CIBA-GEIGY AG (CH) | 1991-09-04 | — | — | EP | claimed |
| US-5171354-A | Herbicides | CIBA-GEIGY CORPORATION (US) | 1992-12-15 | — | — | US | disclosed |
| EP-0445069-A1 | Heterocyclic compounds | CIBA-GEIGY AG (CH) | 1991-09-04 | — | — | EP | disclosed |