Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NQO2 | P16083 | 1/20 | 0.32 |
| ▸ | POLB | P06746 | 2/20 | 0.31 |
| ▸ | MAPT | P10636 | 2/20 | 0.31 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.31 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.31 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.31 |
| ▸ | MEN1 | O00255 | 1/20 | 0.31 |
| ▸ | LMNA | P02545 | 1/20 | 0.31 |
| ▸ | RECQL | P46063 | 1/20 | 0.31 |
| ▸ | MMP14 | P50281 | 1/20 | 0.31 |
| ▸ | GFER | P55789 | 1/20 | 0.31 |
| ▸ | ERN1 | O75460 | 1/20 | 0.31 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.31 |
| ▸ | AKR1C3 | P42330 | 1/20 | 0.31 |
| ▸ | AKR1C2 | P52895 | 1/20 | 0.31 |
| ▸ | AKR1C1 | Q04828 | 1/20 | 0.31 |
| ▸ | GAA | P10253 | 1/20 | 0.31 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.31 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.31 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9730823 | 0.82 | AKR1C3 (0.39) | POLBKMT2AKDM4EMEN1LMNA | |
| SCHEMBL9731139 | 0.78 | NSD2 (0.48) | POLBMAPTMAPK1KMT2AKDM4E | |
| SCHEMBL9731562 | 0.78 | PARP1 (0.36) | KMT2AKDM4ELMNAERN1ALDH1A1 | |
| SCHEMBL9731760 | 0.74 | ERN1 (0.37) | MAPTMAPK1KMT2AKDM4EMEN1 | |
| SCHEMBL31466752 | 0.74 | NR4A1 (0.52) | POLBKMT2AKDM4EMEN1LMNA | |
| SCHEMBL17433761 | 0.74 | NR4A1 (0.52) | POLBKMT2AKDM4EMEN1LMNA | |
| SCHEMBL9730984 | 0.73 | KMT2A (0.33) | POLBMAPTMAPK1KMT2AKDM4E | |
| SCHEMBL9732624 | 0.73 | PTPN1 (0.46) | POLBMAPTMAPK1KMT2AKDM4E | |
| SCHEMBL29950812 | 0.73 | ERN1 (0.42) | POLBMAPTKMT2AKDM4EMEN1 | |
| SCHEMBL1133932 | 0.71 | KDM4E (0.54) | POLBMAPTMAPK1KMT2AKDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5122537-A | Tyrosine kinase inhibitors | FARMITALIA CARLO ERBA S.R.L. (IT) | 1992-06-16 | — | — | US | disclosed |