SCHEMBL9730826

SCHEMBL9730826

COC(C)NC(=O)NOc1cc(Cl)ccc1Cl

nearest known ligand 0.42

Predicted protein targets (top 14)

geneUniProtsupporting neighboursconfidence
MEN1 O00255 4/20 0.42
KMT2A Q03164 4/20 0.42
LPAR1 Q92633 2/20 0.41
ALDH1A1 P00352 3/20 0.40
KDM4E B2RXH2 1/20 0.40
SMN1; SMN2 Q16637 1/20 0.40
MAPT P10636 1/20 0.40
LMNA P02545 2/20 0.39
HPGD P15428 1/20 0.38
NLRP1 Q9C000 1/20 0.38
HTT P42858 1/20 0.37
NPSR1 Q6W5P4 1/20 0.37
ABL1 P00519 1/20 0.37
ACACB O00763 1/20 0.37

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL10486979 0.77 ALDH1A1 (0.47) MEN1KMT2AALDH1A1KDM4ESMN1; SMN2
SCHEMBL9674668 0.75 HTT (0.44) MEN1KMT2ALPAR1ALDH1A1KDM4E
SCHEMBL9673561 0.73 THRB (0.51) MEN1KMT2AALDH1A1KDM4ESMN1; SMN2
SCHEMBL9731148 0.72 APEX1 (0.45) MEN1KMT2AALDH1A1KDM4ESMN1; SMN2
SCHEMBL9731432 0.71 PKM (0.51) MEN1KMT2AALDH1A1KDM4EMAPT
SCHEMBL9730736 0.69 HPGD (0.56) ALDH1A1KDM4ESMN1; SMN2MAPTLMNA
SCHEMBL9730830 0.68 MEN1 (0.46) MEN1KMT2AALDH1A1KDM4ESMN1; SMN2
SCHEMBL12656154 0.67 TSHR (0.50) ALDH1A1KDM4ESMN1; SMN2MAPTLMNA
Trichloroacetic Acid SCHEMBL9730870 0.66 KMT2A (0.41) MEN1KMT2AALDH1A1KDM4ESMN1; SMN2
SCHEMBL9638011 0.66 CXCR1 (0.30) SMN1; SMN2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-5112385-A Useful in rice paddies KUMIAI CHEMICAL INDUSTRY CO., LTD. (JP) 1992-05-12 US disclosed
US-4968341-A PRE-AND POSTEMERGENCE HERBICIDES KUMIAI CHEMICAL INDUSTRY CO. (JP) 1990-11-06 US disclosed
EP-0183174-B1 SUBSTITUTED PHENOXY UREA, PROCESSES FOR ITS PREPARATION AND HERBICIDE CONTAINING IT AS ACTIVE INGREDIENT KUMIAI CHEMICAL INDUSTRY CO., LTD. (JP) 1988-10-26 EP disclosed
EP-0183174-A2 Substituted phenoxy urea, processes for its preparation and herbicide containing it as active ingredient KUMIAI CHEMICAL INDUSTRY CO., LTD. (JP) 1986-06-04 EP disclosed