Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 3/20 | 0.60 |
| ▸ | EGFR | P00533 | 2/20 | 0.60 |
| ▸ | GAA | P10253 | 2/20 | 0.60 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.60 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.60 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.60 |
| ▸ | POLB | P06746 | 1/20 | 0.60 |
| ▸ | PKM | P14618 | 1/20 | 0.60 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.60 |
| ▸ | AR | P10275 | 1/20 | 0.43 |
| ▸ | SYK | P43405 | 1/20 | 0.39 |
| ▸ | ECE2 | P0DPD6 | 2/20 | 0.38 |
| ▸ | ECE1 | P42892 | 2/20 | 0.38 |
| ▸ | MUS81 | Q96NY9 | 2/20 | 0.38 |
| ▸ | MEN1 | O00255 | 1/20 | 0.38 |
| ▸ | MITF | O75030 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.38 |
| ▸ | NCOA1 | Q15788 | 1/20 | 0.38 |
| ▸ | NCOA3 | Q9Y6Q9 | 1/20 | 0.38 |
| ▸ | DAO | P14920 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9320066 | 0.78 | MAPT (0.62) | MAPTEGFRGAATDP1KDM4E | |
| SCHEMBL9320061 | 0.78 | MAPT (0.62) | MAPTEGFRGAATDP1KDM4E | |
| SCHEMBL9732248 | 0.78 | ALDH1A1 (0.46) | MAPTEGFRGAATDP1KDM4E | |
| SCHEMBL9732495 | 0.76 | MAPT (0.53) | MAPTEGFRGAATDP1KDM4E | |
| SCHEMBL9731076 | 0.76 | MAPT (0.53) | MAPTEGFRGAATDP1KDM4E | |
| SCHEMBL9732522 | 0.76 | EGFR (0.55) | MAPTEGFRGAATDP1KDM4E | |
| SCHEMBL669781 | 0.75 | TRIM24 (0.54) | TDP1ARECE2ECE1MUS81 | |
| SCHEMBL31194371 | 0.75 | TRIM24 (0.54) | TDP1ARECE2ECE1MUS81 | |
| SCHEMBL668600 | 0.75 | TRIM24 (0.54) | TDP1ARECE2ECE1MUS81 | |
| SCHEMBL9322697 | 0.75 | EGFR (0.74) | MAPTEGFRGAATDP1KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5122537-A | Tyrosine kinase inhibitors | FARMITALIA CARLO ERBA S.R.L. (IT) | 1992-06-16 | — | — | US | claimed |
| US-5122537-A | Tyrosine kinase inhibitors | FARMITALIA CARLO ERBA S.R.L. (IT) | 1992-06-16 | — | — | US | disclosed |